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Record W4307627826 · doi:10.5281/zenodo.7264066

Optimised DNA isolation from marine sponges for natural sampler DNA (nsDNA) metabarcoding

2022· article· en· W4307627826 on OpenAlexaff
Lynsey R. Harper, Erika F. Neave, Graham S. Sellers, Alice V. Cunnington, María Belén Arias, Jamie Craggs, Barry MacDonald, Ana Riesgo, Stefano Mariani

Bibliographic record

VenueZenodo (CERN European Organization for Nuclear Research) · 2022
Typearticle
Languageen
FieldEnvironmental Science
TopicEnvironmental DNA in Biodiversity Studies
Canadian institutionsFisheries and Oceans Canada
FundersNatural Environment Research CouncilSight Research UK
KeywordsIsolation (microbiology)SpongeDNABiologyAncient DNANatural (archaeology)Environmental DNADNA extractionComputational biologyGeneticsEcologyMicrobiologyPolymerase chain reactionBiodiversityPaleontologyGeneMedicine

Abstract

fetched live from OpenAlex

Data repository accompanying the paper 'Optimised DNA isolation from marine sponges for natural sampler DNA (nsDNA) metabarcoding' by Harper et al. (2022). 1_Raw_Data.zip This zipped folder contains the Jupyter notebook and sample_accessions.tsv file required to download raw illumina data from the NCBI Sequence Read Archive: BioProject: PRJNA854174 BioSample accessions: SAMN29421799 - SAMN29421894 (Phase 1) and SAMN29444657 - SAMN29444784 (Phase 2) SRA accessions: SRR19906974 - SRR19907069 (Phase 1) and SRR19912485 - SRR19912613 (Phase 2) 2_Reference_Databases.zip This zipped folder contains scripts used to generate curated reference databases used for taxonomic assignment in GenBank/fasta format. 3_Tapirs.zip This zipped folder contains the scripts and files needed to perform bioinformatic processing with Tapirs. In order to make use of scripts, you will have to install Tapirs and its dependencies. Please see the Tapirs GitHub repository for instructions on how to do this. 4_Data_Analysis.zip This zipped folder contains all scripts and metadata required to produce figures and statistically analyse data in R. Please contact Dr Lynsey Harper (lynsey.harper2@gmail.com) if you encounter any issues!

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.010
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.110
Threshold uncertainty score0.369

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.010
Meta-epidemiology (narrow)0.0020.002
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0030.003
Science and technology studies0.0010.001
Scholarly communication0.0020.001
Open science0.0030.003
Research integrity0.0010.003
Insufficient payload (model declined to judge)0.1100.128

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.031
GPT teacher head0.216
Teacher spread0.185 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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Same venueZenodo (CERN European Organization for Nuclear Research)→Same topicEnvironmental DNA in Biodiversity Studies→French-language works237,207→