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Assessment of cognitive functions in middle-aged patients with type 2 diabetes

2022· article· en· W4308267913 on OpenAlexaboutno aff
V. I. Velychko, V.L. Mykhailenko, Yе. O. Tuliantseva, D.O. Lahoda, H.O. Danylchuk, Yu.G. Tsyunchyk

Bibliographic record

VenueReproductive Endocrinology · 2022
Typearticle
Languageen
FieldNeuroscience
TopicNeurological Disorders and Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsMontreal Cognitive AssessmentMedicineBody mass indexInternal medicineAnxietyDiabetes mellitusBeck Depression InventoryType 2 diabetesHospital Anxiety and Depression ScaleObesityDepression (economics)Type 2 Diabetes MellitusPhysical therapyCognitive impairmentEndocrinologyPsychiatryDisease

Abstract

fetched live from OpenAlex

Objectives: to evaluate cognitive functions in middle-aged patients with type 2 diabetes mellitus (T2DM).Materials and methods. The total number of participants was 72 people. The main group included 52 patients with T2DM (25 women, 27 men), the control group included 20 people (11 women, 9 men) without T2DM and without carbohydrate metabolism disorders.Cognitive function was assessed using the following scales: the Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA). Anxiety-depressive disorders were assessed using self-administered questionnaires: the Hospital Anxiety and Depression Scale (HADS) and the Beck’s Depression Inventory scale.Results. In the main group the average duration of T2DM was 8.31 ± 0.53 years, the average HbA1c level was 8.14 ± 0.07%, the fasting glycemia level was 7.07 ± 0.11 mmol/l, average body mass index (BMI) – 28.45 ± 0.60 kg/m2. 18 patients in this group had a normal body weight with an average BMI 23.58 ± 0.26 kg/m2, 12 people had an excessive body weight with an average BMI 28.21 ± 0.43 kg/m2, 22 patients had obesity of various severities with an average BMI 32.57 ± 0.51 kg/m2. The following results were obtained in patients with T2DM according to the MMSE scale: 54% (n = 28) of patients had no cognitive impairment (CI), 46% (n = 24) had various degrees of СІ, of which 27% (n = 14) had mild degree CI, 19% (n = 10) had moderate severity CI. According to the MoCA scale, cognitive deficit was found in 44% of the participants of the main group. According to the Beck’s scale, the following data were obtained: 10 (20%) people had no signs of depression, 34 (65%) of the respondents had signs of subclinical depression, 3 (15%) had signs of clinically expressed depression.Conclusions. We established a direct, close relationship between BMI and HbA1c level according to Spearman’s rank correlation coefficient (ρ = 0.730). When CI is detected, the doctor should review the treatment plan for such patients, avoiding complex management plans that overload patients physically, emotionally, or financially, and will not be implemented to the required extent due to cognitive deficits.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.393

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.036
GPT teacher head0.273
Teacher spread0.237 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations1
Published2022
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Has abstractyes

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