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Changes in mammography screening in Ontario and Alberta following national guideline dissemination: an interrupted time series analysis

2022· preprint· en· W4308432241 on OpenAlexafffundabout
Christine Fahim, Natasha Wiebe, Rosane Nisenbaum, Jemila S. Hamid, Joycelyne Ewusie, Marcello Tonelli, Paula Brauer, Elizabeth Shaw, Neil R. Bell, Dawn Stacey, Nathalie M. Holmes, Sharon E. Straus

Bibliographic record

VenueF1000Research · 2022
Typepreprint
Languageen
FieldMedicine
TopicGlobal Cancer Incidence and Screening
Canadian institutionsPublic Health Agency of CanadaOttawa HospitalMcMaster UniversityUniversity of CalgaryUniversity of OttawaUniversity of GuelphSt. Joseph’s Healthcare HamiltonPublic Health OntarioUniversity of TorontoUniversity of AlbertaSt. Michael's Hospital
FundersCanadian Institutes of Health Research
KeywordsMedicineMammographyResidenceDemographyBreast cancerGerontologyInternal medicineCancer

Abstract

fetched live from OpenAlex

<ns3:p> <ns3:bold>Background:</ns3:bold> In November 2011, the Canadian Task Force on Preventive Health Care released guidelines for screening women at average breast cancer risk. Weak recommendations (framed using GRADE methodology) were made for screening women aged 50 to 74 years every two to three years, and for not screening women aged 40 to 49 years. </ns3:p> <ns3:p/> <ns3:p> <ns3:bold>Methods:</ns3:bold> We conducted an interrupted time series analysis using administrative data to examine bilateral mammography use before and after a release of a national breast screening guideline. Women aged 40 to 74 years living in Ontario or Alberta from 30th November 2008 to 30th November 2014 were included. Strata included age, region of residence, neighbourhood income quintile, immigration status, and education level. </ns3:p> <ns3:p/> <ns3:p> <ns3:bold>Results:</ns3:bold> In both provinces, mammography use rates were lower in the post-intervention period (527 vs. 556 and 428 vs. 465/1000 women in Ontario and Alberta, respectively). In Ontario, mammography trends decreased following guideline release to align with recommendations for women aged 40 to 74 (decrease of 2.21/1000 women, SE 0.26/1000, p&lt;0.0001). In Alberta, mammography trends decreased for women aged 40 to 49 years (3/1000 women, SE 0.32, p&lt;0.001) and 50 to 69 (2.9/1000 women, SE 0.79, p&lt;0.001), but did not change for women aged 70 to 74 (0.7/1000 women, SE 1.23, p=0.553). In both provinces, trends in mammography use rates were sustained for up to three years after guideline release. </ns3:p> <ns3:p/> <ns3:p> <ns3:bold>Conclusions:</ns3:bold> We observed a decrease in screening for women aged 40-49. Additional research to explore whether shared decision making was used to optimize guideline-concordant screening for women aged 50-74 is needed. </ns3:p>

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.620
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0030.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0050.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.101
GPT teacher head0.425
Teacher spread0.325 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2022
Admission routes3
Has abstractyes

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