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Record W4309475162 · doi:10.1038/s41467-022-34234-4

Developing medical imaging AI for emerging infectious diseases

2022· article· en· W4309475162 on OpenAlexaff
Shih-Cheng Huang, Akshay Chaudhari, Curtis P. Langlotz, Nigam H. Shah, Serena Yeung, Matthew P. Lungren

Bibliographic record

VenueNature Communications · 2022
Typearticle
Languageen
FieldMedicine
TopicCOVID-19 diagnosis using AI
Canadian institutionsArtificial Intelligence in Medicine (Canada)
FundersU.S. National Library of MedicineNational Heart, Lung, and Blood InstituteStanford Bio-XSchool of Medicine, Stanford UniversityU.S. Department of Health and Human Services
KeywordsSoftware deploymentWorkflowCoronavirus disease 2019 (COVID-19)Context (archaeology)Data scienceComputer sciencePandemicHealth careStrengths and weaknessesApplications of artificial intelligenceInfectious disease (medical specialty)Artificial intelligenceMedicineDiseasePathologyPsychologySoftware engineeringPolitical science

Abstract

fetched live from OpenAlex

Advances in artificial intelligence (AI) and computer vision hold great promise for assisting medical staff, optimizing healthcare workflow, and improving patient outcomes. The COVID-19 pandemic, which caused unprecedented stress on healthcare systems around the world, presented what seems to be a perfect opportunity for AI to demonstrate its usefulness. However, of the several hundred medical imaging AI models developed for COVID-19, very few were fit for deployment in real-world settings, and some were potentially harmful. This review aims to examine the strengths and weaknesses of prior studies and provide recommendations for different stages of building useful AI models for medical imaging, among them: needfinding, dataset curation, model development and evaluation, and post-deployment considerations. In addition, this review summarizes the lessons learned to inform the scientific community about ways to create useful medical imaging AI in a future pandemic. Very few of the COVID-19 ML models were fit for deployment in real-world settings. In this Comment, Huang et al. discuss the main steps required to develop clinically useful models in the context of an emerging infectious disease.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.014
metaresearch head score (Gemma)0.044
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.014
Threshold uncertainty score0.072

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0140.044
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0030.001
Science and technology studies0.0010.001
Scholarly communication0.0050.005
Open science0.0030.003
Research integrity0.0020.004
Insufficient payload (model declined to judge)0.0050.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.400
Teacher spread0.374 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations40
Published2022
Admission routes1
Has abstractyes

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