A Comparative Study of Combined Effect of Dermaroller and Topical Tacrolimus (50 Cases) vs Topical Tacrolimus Alone (50 Cases) in Patients of Stable Vitiligo (Total 100 Cases)
Bibliographic record
Abstract
Background: Vitiligo is an autoimmune disease produced as a result of interaction of environmental, genetic, neural factors, leading to the destruction of melanocytes and appearance of depigmented macules. It is a chronic disease of great cosmetic concern. As it is often recalcitrant to medical treatment alone, many surgical techniques are used to treat stable vitiligo. Aims and objectives: To evaluate the efficacy and safety of combined dermaroller and topical tacrolimus versus topical tacrolimus alone treatment in the patients of stable vitiligo. Materials and Methods: Material:Dermaroller specification :192needles, 1.5 mm diameter Method: Patients were randomly assigned into two groups of 50 patients each. Group A received treatment with dermaroller followed by topical tacrolimus whereas Group B received treatment with topical tacrolimus alone. In both the groups, standard medical treatment was also given. Standard digital photographs were taken at each visit to support the data. Results: The dermaroller group showed maximum patients with excellent response in 44% cases as compared to topical tacrolimus alone group which showed excellent response in 24% cases. Limitations: small sample size and absence of control group were the main limitations of our study. Conclusion: Dermaroller is safe and effective tool for repigmentation in vitiligo with minimum side effects for transdermal drug delivery. Keywords: Vitiligo, Dermaroller, Tacrolimus
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".