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Record W4310099972 · doi:10.1016/j.jaci.2022.10.021

The diagnosis of severe combined immunodeficiency: Implementation of the PIDTC 2022 Definitions

2022· article· en· W4310099972 on OpenAlexaff
Christopher C. Dvorak, Élie Haddad, Jennifer Heimall, Elizabeth Dunn, Morton J. Cowan, Sung‐Yun Pai, Neena Kapoor, Lisa Forbes Satter, Rebecca H. Buckley, Richard J. O’Reilly, Sharat Chandra, Jeffrey J. Bednarski, Olatundun Williams, Ahmad Rayes, Theodore B. Moore, Christen L. Ebens, Blachy J. Dávila Saldaña, Aleksandra Petrović, Deepak Chellapandian, Geoff D.E. Cuvelier, Mark T. Vander Lugt, Emi Caywood, Shanmuganathan Chandrakasan, Hesham Eissa, Frederick D. Goldman, Evan Shereck, Victor M. Aquino, Kenneth B. DeSantes, Lisa Madden, Holly Miller, Lolie C. Yu, Larisa Broglie, Alfred P. Gillio, Ami J. Shah, Alan P. Knutsen, Jeffrey Andolina, Avni Y. Joshi, Paul Szabolcs, Malika Kapadia, Caridad Martinez, Roberta E. Parrot, Kathleen E. Sullivan, Susan E. Prockop, Roshini S. Abraham, Monica S. Thakar, Jennifer W. Leiding, Donald B. Kohn, Michael A. Pulsipher, Linda M. Griffith, Luigi D. Notarangelo, Jennifer M. Puck

Bibliographic record

VenueJournal of Allergy and Clinical Immunology · 2022
Typearticle
Languageen
FieldImmunology and Microbiology
TopicImmunodeficiency and Autoimmune Disorders
Canadian institutionsCancerCare ManitobaUniversité de MontréalUniversity of ManitobaCentre Hospitalier Universitaire Sainte-Justine
FundersNHLBI Division of Intramural ResearchNational Center for Advancing Translational SciencesNational Institute of Allergy and Infectious DiseasesNational Heart, Lung, and Blood InstituteOffice of Naval ResearchHealth Resources and Services AdministrationNational Cancer InstituteU.S. Department of Health and Human ServicesNational Institutes of HealthNational Institute of Neurological Disorders and StrokeCalifornia Institute of Regenerative Medicine
KeywordsHuman immunodeficiency virus (HIV)MedicineComputer scienceVirology

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.619
Threshold uncertainty score0.899

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.001
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.296
Teacher spread0.272 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations39
Published2022
Admission routes1
Has abstractno

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