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Record W4312198003 · doi:10.1101/2022.12.26.521929

“Quasigenus” among <i>Phycodnaviridae</i> : A diversity of chlorophyte-infecting viruses in response to a dense algal culture in a high-rate algal pond

2022· preprint· en· W4312198003 on OpenAlexaff
Emily E. Chase, Thomas M. Pitot, Sonia Monteil-Bouchard, Christelle Desnues, Guillaume Blanc

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2022
Typepreprint
Languageen
FieldEnvironmental Science
TopicMicrobial Community Ecology and Physiology
Canadian institutionsUniversité Laval
FundersOffice of ScienceAgence Nationale de la RechercheAix-Marseille UniversitéJoint Genome InstituteInstitut Français de Recherche pour l'Exploitation de la MerEuropean CommissionU.S. Department of Energy
KeywordsBiologyAlgaeAlgal bloomViral quasispeciesChlorophytaHost (biology)MetagenomicsGiant VirusVirusUlvophyceaeBotanyEcologyPhytoplanktonGenomeGeneGeneticsNutrient

Abstract

fetched live from OpenAlex

Abstract This study approaches a high rate algal pond (HRAP) culture by metagenomic sequencing of the viral DNA fraction, this includes the so-called giant virus fraction (phylum Nucleocytoviricota ), with the goal of revealing viruses coexisting within an intensified algal culture. A wealth of interesting novel viruses is revealed, including members of Nucleocytoviricota, Lavidaviridae , and polinton-like viruses, which are taxa containing previously characterized algal viruses. Our sequencing results are coupled with a virus targeted qPCR study and 18S rDNA metabarcoding to elucidate potential virus-host interactions. Several species of green algae are identified (Chlorophyta), likely representing the alternating dominant populations during the year of study. Finally, we observe a bloom of viral diversity within the family Phycodnaviridae ( Nucleocytoviricota ), including highly related but non-identical genotypes, appearing in the HRAP in September and October 2018. This bloom is most likely the cause of a mass mortality event of the cultured algae that occurred during these same months. We hypothesize that these related Phycodnaviridae lineages selectively infect different strains of the same algal species of the Genus Picochlorum that have been identified in the HRAP by metabarcoding and coined this phenomenon a “quasigenus” by analogy to the RNA virus quasispecies concept.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.220
Teacher spread0.208 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2022
Admission routes1
Has abstractyes

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