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Record W4312411032 · doi:10.21608/azjp.2022.268936

VISUAL EVOKED POTENTIAL & ELECTRORETINOGRAM RESULTS IN PREVIOUSLY VENTILATED PRETERM INFANTS

2022· article· en· W4312411032 on OpenAlexaff
Mohamed Abd, El-Fatah El-Khouly, Taha El-Keʼiy, Abd El-Magid, Mohamed Tag El-Din, Amira M. El Gohary, Mohsen Taha Elkeiy

Bibliographic record

VenueAl-Azhar Journal of Pediatrics · 2022
Typearticle
Languageen
FieldMedicine
TopicOcular and Laser Science Research
Canadian institutionsPediatric Oncology Group
Fundersnot available
KeywordsRetinopathy of prematurityMedicineCognitionErgAudiologyRetinalAffect (linguistics)PsychologyEvoked potentialPediatricsDevelopmental psychologyOphthalmologyNeuroscienceGestational agePregnancyCommunication

Abstract

fetched live from OpenAlex

Background: Previously ventilated preterms are at a high risk of abnormal visual and neurological development when compared to full term babies and non-ventilated preterms. Preterm birth is associated with retinopathy of prematurity and can also affect the development of brain structures associated with post-retinal processing of visual information. These impairments can continue into adolescence and adulthood and may contribute to the difficulties in learning, attention, behavior and cognition that some children born preterm experience. Electrophysiologic testing of the visual system requires primarily the ERG &VEP which useful in the diagnosis of visual loss in nonverbal patients especially in children. Aim of the work: we aim to assess the VEP and ERG in previously ventilated preterm infants. Subject and Method: this study is prospective case control study. The study was conducted on 100 preterm babies, male and female, less than 37week gestational age. The average age from 1 to 6 months with normal fundus examination. Half of them (50 babies) previously ventilated preterms as case group and 50 babies as control. this work was done for Preterms at Bostan Diagnostic Eye Center "Cairo-Egypt" from October 2021 to March 2022.VEP and ERG was done for each eye separately according to the International Society for Clinical Electrophysiology of Vision (ISCEV) standards protocols. Results: There was a statistically significant association between groups and flash VEP, p value (<0.001). VEP absent in 90% of case group (preterms previously ventilated). A strong positive correlation between oculus dextrus (OD=RT Eye) flash ERG photopic b wave amplitude in microvolt and duration on mechanical ventilation by day among ventilated patients. A strong positive correlation between oculus sinister (OS=LT Eye) flash ERG photopic a wave latency in ms and age by months among ventilated patients. A moderate negative correlation between OD eye flash ERG photopic b wave amplitude in microvolt and gestational age by weeks among ventilated patients. A moderate positive correlation between OS eye flash erg scotopic 3.0 b wave amplitude in microvolt and duration on mechanical ventilation by day among ventilated patients. A weak positive correlation between OS eye flash ERG photopic b wave amplitude in microvolt and duration on mechanical ventilation by day among ventilated patients. Conclusion: the result obtained by our study provide that VEP test in previously ventilated preterms was absent in 90% of cases. A strong positive correlation between OD eye flash ERG photopic b wave amplitude in microvolt and duration on mechanical ventilation by day among ventilated patients p-value (0.0019) and correlation coefficient (0.429). A strong positive correlation between OS eye flash ERG photopic a wave latency in ms and age by months among ventilated patients p-value (0.0018) and correlation coefficient (0.43).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.068
Threshold uncertainty score0.575

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.325
Teacher spread0.311 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2022
Admission routes1
Has abstractyes

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