Romosozumab verbessert vertebrale kortikale Knochenmasse und -struktur im Vergleich zu Teriparatid signifikant: HR-QCT-Analyse aus randomisierter Studie bei postmenopausalen Frauen mit niedriger BMD
Bibliographic record
Abstract
Einleitung Das Verständnis der Wirkung von Osteoporosetherapien an der Wirbelsäule ist für die Knochenbiologie und die klinische Praxis von großer Bedeutung. Wir haben ein verbessertes Verfahren entwickelt, das auf einer komplexe 3D-Segmentierung des Wirbelkörperkortex auf hochauflösenden quantitativen Computertomografiescans (HR-QCT) von T12-Wirbelkörpern basiert, um spezifische Veränderungen der Knochenmineraldichte (BMD) und der Mikrostruktur zu bestimmen.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.002 | 0.002 |
| Meta-epidemiology (broad) | 0.003 | 0.001 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.002 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.002 | 0.004 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.004 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; both teacher heads agree on what is shown here.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".