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Record W4313299873 · doi:10.53350/pjmhs20221611287

Intraocular Pressure Control after Trabeculectomy: A Comparison of Mitomycin C and Bevacizumab

2022· article· en· W4313299873 on OpenAlexaff
Aftab Ahmed Khan, Sohail Ahmed Siddiqui, Mujahid Raza, Nisar Khan

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldMedicine
TopicGlaucoma and retinal disorders
Canadian institutionsContinental (Canada)
Fundersnot available
KeywordsTrabeculectomyIntraocular pressureMedicineBevacizumabMitomycin CGonioscopyOphthalmologySurgeryRandomized controlled trialChemotherapy

Abstract

fetched live from OpenAlex

Objective: To analyze and compare the role of mitomycin C and bevacizumab in reducing the intraocular pressure post trabeculectomy. Study Design: Comparative analytical study Place and Duration of Study: Department of Ophthalmology, Indus Medical College, Tando Mohammad Khan from 1st October 2021 to 31st March 2022. Methodology: Sixty patients were enrolled. Patients were divided equally in two groups. Thirty patients were given mitomycin C in Group A while Group B were those 30 patients who were given bevacizumab in a randomized manner. All the cases underwent trabeculectomy and followed upto a year and results were compared. An examination using slit lamp biomicroscope was performed for thorough examination of anterior segments with intraocular pressure recording. Gonioscopy through Goldman-two mirror lens was conducted. Results: The mean age of the patients was 50.23±7.7 years with 41.6 % females and 58.3% males. The intraocular pressure was seen to be controlled in 23 patients at day 1 in Group A and 23 patients in group B. The comparative analysis of pre and post intraocular pressure after trabeculectomy has presented the significant reduction in Group A than Group B at day 1, 6th week as well as at 3rd month or 6th moth to a year. Conclusion: Mitomycin C as well as bevacizumab are highly effective in reducing intraocular pressure post trabeculectomy with mitomycin C being slightly better in efficacy than bevacizumab. Keywords: Intraocular pressure, Trabeculectomy, Effective, Efficacy

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Non-randomized trial · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.005
GPT teacher head0.246
Teacher spread0.241 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNon-randomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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