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Regulation of body temperature in Canadian beef cattle of various immune response phenotypes when the temperature humidity index is above normal

2020· article· en· W4313368990 on OpenAlexaffabout
Nasrin Husseini, Tess Altvater-Hughes, Shannon C Beard, Douglas C. Hodgins, Bonnie A. Mallard

Bibliographic record

VenueThe Journal of Immunology · 2020
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicEffects of Environmental Stressors on Livestock
Canadian institutionsUniversity of Guelph
Fundersnot available
KeywordsImmune systemAnimal scienceBiologyHeat indexBeef cattleReproductionRectal temperatureRespiration rateAntibodyHumidityImmunologyRespirationEcologyHeat stressBotany

Abstract

fetched live from OpenAlex

Abstract Climate change with increases in ambient temperature and humidity, affect animal life dramatically decreasing their production and reproduction potential, as well as making them more susceptible to different diseases. This leads to an increase in their core body temperature and respiration rate which in turn decreases their production, reproduction, and immune function. The High Immune Response (HIR™) technology which has been developed at the University of Guelph ranks animals using two arms of adaptive immune system to high (H), average (A), and low (L) immune responders. (H) immune responders have been reported to have fewer incidents of disease and robust immune response. (H) immune responders have been also reported to have better colostrum and milk quality making them an ideal model to examine the effects of climate change on health traits. The objective of this study was to check if (H) immune responder beef cattle are able to regulate their rectal temperature better. In this study, rectal temperatures of 36 beef cows were recorded during normal Temperature-Humidity Index (THI<74) and above normal THI (THI ≥ 74) once in the morning and once in the afternoon. Results indicated that 62.5% of cows showed increases in rectal temperature in THI ≥ 74. However, mean rectal temperatures of (H) antibody-mediated immune responders did not differ significantly during THI < 74 and THI ≥ 74; indicating that these high antibody responder beef cows were better able to regulate their body temperatures. This is the first time that genetic regulation of an immune response trait has been shown to influence the response to in vivo heat stress indicating that it may be possible to select cattle with both improved health and heat tolerance.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.682
Threshold uncertainty score0.631

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.194
Teacher spread0.188 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2020
Admission routes2
Has abstractyes

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