Histopathological carcinoma classification using parallel, cross‐concatenated and grouped convolutions deep neural network
Bibliographic record
Abstract
Abstract Cancer is more alarming in modern days due to its identification at later stages. Among cancers, lung, liver and colon cancers are the leading cause of untimely death. Manual cancer identification from histopathological images is time‐consuming and labour‐intensive. Thereby, computer‐aided decision support systems are desired. A deep learning model is proposed in this paper to accurately identify cancer. Convolutional neural networks have shown great ability to identify the significant patterns for cancer classification. The proposed Parallel, Cross Concatenated and Grouped Convolutions Deep Neural Network (PC2GCDN2) has been developed to obtain accurate patterns for classification. To prove the robustness of the model, it is evaluated on the KMC and TCGA‐LIHC liver dataset, LC25000 dataset for lung and colon cancer classification. The proposed PC2GCDN2 model outperforms states‐of‐the‐art methods. The model provides 5.5% improved accuracy compared to the LiverNet proposed by Aatresh et. al on the KMC dataset. On the LC25000 dataset, 2% improvement is observed compared to existing models. Performance evaluation metrics like Sensitivity, Specificity, Recall, F1‐Score and Intersection‐Over‐Union are used to evaluate the performance. To the best of our knowledge, PC2GCDN2 can be considered as gold standard for multiple histopathology image classification. PC2GCDN is able to classify the KMC and TCGA‐LIHC liver dataset with 96.4% and 98.6% accuracy, respectively, which are the best results obtained till now. The performance has been superior on LC25000 dataset with 99.5% and 100% classification accuracy on lung and colon dataset, by utilizing less than 0.5 million parameters.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".