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Record W4316465850 · doi:10.5114/dr.2022.123985

Paclitaxel-induced pseudoscleroderma

2022· article· en· W4316465850 on OpenAlexaboutno aff
Krzysztof Sadko, Anna Płaszczyńska, Justyna Czarny

Bibliographic record

VenueDermatology Review · 2022
Typearticle
Languageen
FieldMedicine
TopicSystemic Sclerosis and Related Diseases
Canadian institutionsnot available
Fundersnot available
KeywordsPaclitaxelDermatologyMedicineInternal medicineChemotherapy

Abstract

fetched live from OpenAlex

Introduction: Pseudoscleroderma (scleroderma-like disease) is a group of rare and chronic skin conditions that mimics systemic sclerosis.The etiology of these diseases covers a wide range of causative factors, including drugs used in chemotherapy.Case report: A 78-year-old woman was admitted due to significant hardening of the skin in the dorsal surface of feet and distal part of the lower legs.These lesions occurred after a concluded chemotherapy with paclitaxel for right breast cancer.Treatment with pentoxifylline, topical clobetasol and 30% urea ointment was introduced.One month later an improvement in the clinical condition was observed.Conclusions: We present a case of pseudoscleroderma caused by paclitaxel and successfully treated with pentoxifylline and topical clobetasole.Conclusion of the treatment course with paclitaxel may have positively influenced the outcome in this treatment.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.013
Threshold uncertainty score0.042

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0130.005

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.037
GPT teacher head0.299
Teacher spread0.262 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2022
Admission routes1
Has abstractyes

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