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Record W4316813247 · doi:10.1007/s00535-023-01955-2

Prognostic role of detailed colorectal location and tumor molecular features: analyses of 13,101 colorectal cancer patients including 2994 early-onset cases

2023· article· en· W4316813247 on OpenAlex
Tomotaka Ugai, Naohiko Akimoto, Koichiro Haruki, Tabitha A. Harrison, Yin Cao, Conghui Qu, Andrew T. Chan, Peter T. Campbell, Sonja I. Berndt, Daniel D. Buchanan, Amanda J. Cross, Brenda Diergaarde, Steven Gallinger, Marc J. Gunter, Sophia Harlid, Akihisa Hidaka, Michael Hoffmeister, Hermann Brenner, Jenny Chang‐Claude, Li Hsu, Mark A. Jenkins, Yi Lin, Roger L. Milne, Vı́ctor Moreno, Polly A. Newcomb, Reiko Nishihara, Mireia Obón‐Santacana, Rish K. Pai, Lori C. Sakoda, Robert E. Schoen, Martha L. Slattery, Wei Sun, Efrat L. Amitay, Elizabeth Alwers, Stephen N. Thibodeau, Amanda E. Toland, Bethany Van Guelpen, Syed Hassan Ejaz Zaidi, John D. Potter, Jeffrey A. Meyerhardt, Marios Giannakis, Mingyang Song, Jonathan A. Nowak, Ulrike Peters, Amanda I. Phipps, Shuji Ogino

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueJournal of Gastroenterology · 2023
Typearticle
Languageen
FieldMedicine
TopicColorectal Cancer Treatments and Studies
Canadian institutionsLunenfeld-Tanenbaum Research InstituteOntario Institute for Cancer ResearchUniversity of TorontoMount Sinai Hospital
FundersOffice of Research Infrastructure Programs, National Institutes of HealthNational Cancer InstituteMedical Research CouncilCenters for Disease Control and PreventionInstitut Gustave-RoussyDeutsche KrebshilfeWorld Health OrganizationEuropean CommissionWellcome TrustFred Hutchinson Cancer Research CenterDeutsches KrebsforschungszentrumInstitut National de la Santé et de la Recherche MédicaleLigue Contre le CancerBundesministerium für Bildung und ForschungVetenskapsrådetCancer Research UKNational Institutes of HealthU.S. Department of Health and Human Services
KeywordsColorectal cancerMicrosatellite instabilityInternal medicineKRASMedicineCecumRectumOncologySurgical oncologyHazard ratioHepatologyCancerSigmoid colonGastroenterologyConfidence intervalBiologyAlleleMicrosatellite

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.018
Threshold uncertainty score0.534

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.316
Teacher spread0.296 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it