Antioxidant, anti-inflammatory and anticancer activities of Tunisian halophyte Suaeda mollis
Bibliographic record
Abstract
The aim of this study was to investigate the antioxidant, anti-inflammatory, and anticancer properties of Tunisian Suaeda mollis specie after fractionation by increasing polarity of several extracts (Hexane, Dichloromerthane, Methanol and water). Water and methanol extracts of S. mollis exhibited the best in vitro antioxidant ability (2.92±0.19 and 2.77±0.21 µmol TE/mg, respectively), while, dichloromethane extract displayed the highest ex vivo antioxidant activity with an IC50 equal to 1.73 µg/ml. Besides, hexane extract showed an important anti-inflammatory effect inhibiting NO with 55.9% at 160 µg/ml. Finally, dichloromethane extract displayed a potent anticancer activity against cancerous cells A-549 with an IC50 equal to 70±7 µg/ml as well as non cancerous cells Detroit-551 and WS1 (IC50=81±1 and 62±5 µg/ml, respectively) using resazurin test. Moreover, hexane extract is efficient against Caco-2 (IC50=122 µg/ml). Overall, the results suggested that biological activities are influenced by solvent polarity and extractability.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".