Implementation of weekday <scp>time‐restricted</scp> eating to improve metabolic health in breast cancer survivors with overweight/obesity
Bibliographic record
Abstract
Abstract Objective This study aimed to evaluate the implementation of telephone‐based delivery of weekday‐only time‐restricted eating (TRE), its preliminary efficacy for metabolic outcomes, and concurrent lifestyle changes. Methods Twenty‐two breast cancer survivors aged 60+ years with overweight/obesity completed an 8‐week feasibility study of 12 to 8 p.m. weekday‐only ad libitum TRE. The intervention was delivered by one registered dietitian call, twice‐daily automated text messages asking about eating start and stop times, and three support phone calls. Magnetic resonance imaging, venipuncture, and 3 days of diet records and accelerometry were performed at baseline and after intervention. Results Participants had a mean age of 66 (SD 5) years with BMI of 31.8 (4.8) kg/m 2 . Intervention implementation was successful, including excellent adherence (98%), participant acceptability, and a low symptom profile and cost ($63/participant). There were no significant changes in individual components of metabolic syndrome, lipid profile, or hemoglobin A 1c , despite clinically relevant changes occurring within individual participants. Magnetic resonance imaging–derived hepatic steatosis and thigh myosteatosis did not change. Dietary intake changes included reduced energy (−22%) and protein (−0.2 g/kg). Physical activity and sleep did not change. Conclusions Eight weeks of telephone‐delivered weekday TRE is a feasible, acceptable, low‐symptom, and low‐cost intervention. Future studies may consider a longer intervention length for more consistent metabolic improvements and counseling to enhance protein intake.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.002 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".