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Record W4319066719 · doi:10.1016/j.lana.2023.100437

The continuous opioid death crisis in Canada: changing characteristics and implications for path options forward

2023· article· en· W4319066719 on OpenAlexafffundabout
Benedikt Fischer

Bibliographic record

VenueThe Lancet Regional Health - Americas · 2023
Typearticle
Languageen
FieldMedicine
TopicOpioid Use Disorder Treatment
Canadian institutionsSimon Fraser UniversityUniversity of TorontoUniversity of the Fraser Valley
FundersCanadian Institutes of Health Research
KeywordsPath (computing)OpioidEconomicsComputer scienceMedicineInternal medicineComputer network

Abstract

fetched live from OpenAlex

Since 2016, more than 30,000 people have died from opioid-related overdoses in Canada-more than from other, major accidental death causes combined. 1,2pioid deaths have markedly slowed trends in life expectancy and triggered (provincial but not federal) states of public health emergency.More recently, related media headlines and political proclamations ("We will not rest and do everything needed …") have largely disappeared.Yet those who read this muting as a sign of victory in the battle against the longstanding overdose death crisis are misguided.Per recent data, there were 3556 (rate: 19/100,000 population) opioid-related toxicity deaths in the first six months of 2022 -proportionally similar to the total number (7,993) and rate of opioidrelated deaths in 2021. 2 These indicators represent the highest annual tolls of opioid deaths since national Canadian statistics were established (2016); they reflect general patterns observed in the United States (US). 3 After raging and taking-many young-lives at growing levels for more than a decade, the opioid-death crisis is very much alive in Canada; worse yet, it has become widely accepted as a part of everyday reality and therefore embraced as a kind of 'new normal'.There are key evolutionary changes of the opioiddeath crisis that mirror those experienced in the US, which have been characterized as different 'waves' of the epidemic unfolding there. 3Concretely, what began in Canada in the early-2010s largely as spikes in overdose-deaths from potent prescription opioid drugs, by 2015/16 changed into an accelerating death epidemic from mostly illicit, toxic synthetic opioids (e.g., fentanyl/ analogues) distributed across North America. 1 Post-2020, >75%-while with stark regional differences -of opioid deaths in Canada have involved fentanyl. 2However, approximately half or more have also involved a psychostimulant (e.g., methamphetamine or cocaine) substance; moreover, increasing proportions have also

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.016
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.084
Threshold uncertainty score0.606

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.016
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.007
Science and technology studies0.0070.004
Scholarly communication0.0080.004
Open science0.0030.004
Research integrity0.0030.007
Insufficient payload (model declined to judge)0.0110.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.065
GPT teacher head0.358
Teacher spread0.293 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations78
Published2023
Admission routes3
Has abstractno

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