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Record W4319332881 · doi:10.1128/msphere.00022-23

mSphere of Influence: Deterministic and Stochastic Processes Drive Microbial Evolution

2023· article· en· W4319332881 on OpenAlexafffund
Aleeza C. Gerstein

Bibliographic record

VenuemSphere · 2023
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicEvolution and Genetic Dynamics
Canadian institutionsUniversity of Manitoba
FundersNatural Sciences and Engineering Research Council of CanadaGovernment of CanadaCanadian Institute for Advanced Research
KeywordsMicrobial geneticsBiologyEvolutionary biologyField (mathematics)Biochemical engineeringGeneticsMathematicsGeneEngineering

Abstract

fetched live from OpenAlex

Aleeza C. Gerstein works in the field of microbial evolutionary genetics in human fungal pathogens. In this mSphere of Influence article, she reflects on how the papers "Experimental tests of the roles of adaptation, chance, and history in evolution" by Travisano et al. (1995) and "Pervasive genetic hitchhiking and clonal interference in forty evolving yeast populations" by Lang et al. (2013) provided her with a framework for thinking about the competing stochastic and deterministic evolutionary forces that act on microbial populations at the genotypic and phenotypic levels to cause both parallelism and divergence under different scenarios.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.015
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.003
Threshold uncertainty score0.012

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.015
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.000
Science and technology studies0.0010.005
Scholarly communication0.0030.004
Open science0.0010.002
Research integrity0.0020.003
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.004
GPT teacher head0.230
Teacher spread0.226 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes2
Has abstractyes

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