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The Asymmetry Within: A Renewed Look at Cupid’s Bow in Unilateral Cleft Lip

2023· article· en· W4319662485 on OpenAlexaff
Ellie Gschwendtner, Megan Dietze-Fiedler, Matthew R. Smith, John W. Polley

Bibliographic record

VenuePlastic & Reconstructive Surgery Global Open · 2023
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicCleft Lip and Palate Research
Canadian institutionsHospital for Sick ChildrenUniversity of Toronto
Fundersnot available
KeywordsAsymmetryCraniofacialOrthodonticsStatistical analysisGeometryMedicinePhysicsMathematicsStatistics

Abstract

fetched live from OpenAlex

Objective: All unilateral cleft lip (UCL) repair techniques assume and describe a displaced or obliquely rotated Cupid’s bow within the cleft prolabium. This is true, but there is more. A focused anatomic description of the prolabium, and the configuration of Cupid’s bow within the prolabium, in UCL is deficient in the literature. The purpose of this study was to analyze the prolabium in unmanipulated (pre-NAM, pre-surgical) UCL patients, with or without palatal clefts, with emphasis on the size, shape, and symmetry of the Cupid’s bow within the prolabium itself. In addition, a geometric analysis conveys the most efficient location for incisional correction of the “asymmetry within” Cupid’s bow. Methods: Standardized frontal photographs of 37 infants with UCL were studied by experienced craniofacial team members. Cupid’s bow landmarks were identified and prolabial angles (perpendicular through valley to bow height) were recorded on both the cleft and non-cleft sides. Three groups were analyzed (all n=37, complete n=22, incomplete n=15). Unpaired t-test and two-tailed t-test were utilized for statistical analysis. A geometric linear analysis was preformed to show incisional length and location for correction of the asymmetric Cupid’s bow. Results: Significant intrinsic Cupid’s bow asymmetry within the prolabium was present in all groups. This asymmetry was exhibited by significance (p<.0001) between angles in all groups. For all UCL the mean difference between angles was 4.992 degrees. (p<.0001) The largest mean difference was 7.608 degrees (95% CI: 4.927-10.289 degrees; p < 0.0001) in the incomplete group. Conclusions: In UCL not only is the prolabium with its concomitant Cupid’s bow rotated upwards into the cleft, but there exists a significant intrinsic asymmetry of the Cupid’s bow itself within the prolabium. This intrinsically asymmetric Cupid’s bow is then rotated upwards into the cleft itself. This finding has yet to be described in the cleft literature. Furthermore, a linear geometric equation describes incisional locations and lengths within the prolabium for correcting the Cupid’s bow asymmetry. This finding enhances our anatomic understanding of UCL and has significant importance when selecting surgical repair techniques. Corresponding Author: Ellie Gschwendtner, 2365 Orchard Circle Dr. Unit 13, Traverse City, MI 49686

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.019
Threshold uncertainty score0.819

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.297
Teacher spread0.272 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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