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Record W4320490383 · doi:10.1111/cdev.13914

Language and reading impairments are associated with increased prevalence of non-right-handedness

2023· review· en· W4320490383 on OpenAlexafffund
Filippo Abbondanza, Philip S. Dale, Carol A. Wang, Marianna E. Hayiou‐Thomas, Umar Toseeb, Tanner Koomar, Karen Wigg, Yu Feng, Kaitlyn M. Price, Elizabeth N. Kerr, Sharon Guger, Maureen W. Lovett, Lisa J. Strug, Elsje van Bergen, Conor V. Dolan, J. Bruce Tomblin, Kristina Moll, Gerd Schulte‐Körne, Nina Neuhoff, Andreas Warnke, Simon E. Fisher, Cathy L. Barr, Jacob J. Michaelson, Dorret I. Boomsma, Maggie Snowling, Charles Hulme, Andrew Whitehouse, Craig E. Pennell, Dianne F. Newbury, John Stein, Joel B. Talcott, Dorothy Bishop, Silvia Paracchini

Bibliographic record

VenueChild Development · 2023
Typereview
Languageen
FieldNeuroscience
TopicHemispheric Asymmetry in Neuroscience
Canadian institutionsHospital for Sick ChildrenPublic Health OntarioUniversity of TorontoKrembil FoundationUniversity Health Network
FundersH2020 European Research CouncilEunice Kennedy Shriver National Institute of Child Health and Human DevelopmentNational Institute on Deafness and Other Communication DisordersHorizon 2020 Framework ProgrammeNational Health and Medical Research CouncilRoyal SocietyCanadian Institutes of Health ResearchMax-Planck-GesellschaftDeutsche ForschungsgemeinschaftUniversity of BristolMedical Research CouncilHospital for Sick ChildrenNederlandse Organisatie voor Wetenschappelijk OnderzoekWellcome Trust
KeywordsPsychologyDyslexiaAssociation (psychology)Dominance (genetics)Developmental psychologyLateralization of brain functionReading (process)Ocular dominanceLateralityAudiologyCognitionLanguage impairmentLanguage developmentCognitive psychologyPsychiatryMedicineNeuroscienceLinguistics

Abstract

fetched live from OpenAlex

Abstract Handedness has been studied for association with language-related disorders because of its link with language hemispheric dominance. No clear pattern has emerged, possibly because of small samples, publication bias, and heterogeneous criteria across studies. Non-right-handedness (NRH) frequency was assessed in N = 2503 cases with reading and/or language impairment and N = 4316 sex-matched controls identified from 10 distinct cohorts (age range 6–19 years old; European ethnicity) using a priori set criteria. A meta-analysis (N cases = 1994) showed elevated NRH % in individuals with language/reading impairment compared with controls (OR = 1.21, CI = 1.06–1.39, p = .01). The association between reading/language impairments and NRH could result from shared pathways underlying brain lateralization, handedness, and cognitive functions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.712
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.036
GPT teacher head0.308
Teacher spread0.272 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations27
Published2023
Admission routes2
Has abstractyes

Explore more

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