Efficacy of a combination of non-drug therapies in patients with non-dementia vascular cognitive impairment
Bibliographic record
Abstract
Objective : to study the effectiveness of a combination of non-drug methods in the treatment of non-dementia cognitive impairment of vascular etiology. Material and methods . The study involved 60 patients with moderate cognitive impairment of vascular etiology. The patients were divided into two groups: group 1 (n=30, mean age 63.7±8.8 years) received a combination of non-drug methods in the form of cognitive training, physical activity and meal planning for 1 month; patients of the 2nd group (n=30, mean age 64.2±10.7 years) were once informed about the advisability of a healthy diet and maintenance of mental and physical activity. Neuropsychological testing was done at the inclusion stage of the study, immediately after 1 month course of treatment, 6 months and a year after the start of the study. There were no significant differences between the groups in terms of cognitive functions at baseline. Results . After a month of treatment, in the 1st group the results of neuropsychological testing significantly (p<0.05) improved compared to the first visit: Montreal Cognitive Function Assessment Scale (MoCA-test) – from 22.5±2.4 to 23.7±2.8, Trail making test part A – from 56.9±20.1, up to 49.3±21.7; Trail making test part B – from 116.8±47.8 to 93.5±36.3; the Digit Symbol Substitution test (DSST) scores increased from 26.6±9.0 to 28.8±9.0. Categorical and literal fluency increased from 14.9±4.1 to 16.5±4.6 and from 10.0±1.7 to 11.6±1.9, respectively. In the 2nd group, 1 month after the start of the study, there were no significant differences from the baseline in neuropsychological tests. Differences between the groups at the second visit were statistically significant (p<0.05) according to the MoCA test, Trail making tests (parts A, B), DSST, and association tests. Significant differences between groups persisted during the first 6 months, but disappeared after 12 months of follow-up. Conclusion . Multimodal non-drug therapy in patients with moderate cognitive impairment of vascular etiology improves the main cognitive parameters.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".