TLP 744 ADENOMAS COLORRECTALES Y MAFLD: UN ESTUDIO TRANSVERSAL EN UNA COHORTE HISPANA DE CRIBADO
Bibliographic record
Abstract
Introduccin: Recientemente, se ha propuesto una nueva definicin de la enfermedad por hgado graso [i.e., enfermedad del hgado graso asociada a disfuncin metablica (MAFLD, por sus siglas en ingls)]. La presencia de enfermedad del hgado graso se asocia a un mayor riesgo de presentar adenomas colorrectales (ACR). No existe informacin respecto a la asociacin de ACR en pacientes hispanos con MAFLD. Objetivo: evaluar la relacin entre MAFLD y el riesgo de CRA en una cohorte chilena. Mtodos: Se estudi a pacientes sometidos a una colonoscopia de tamizaje con estudio imagenolgico abdominal disponible. Se realiz un anlisis de regresin (uni/multivariado de los datos sociodemogrficos y clnicos. Resultados: Se incluyeron 895 pacientes; (42% eran hombres; edad media de 59,9 9,3 aos). El 37,8% (338) tenan ACR. Comparados con los sujetos controles, los pacientes con ACR eran predominantemente hombres (48,2% vs. 38,2%, P = 0,002), tenan mayor edad (61,6 8,7 aos vs. 58,9 9,5 aos, P < 0,001) y presentaban un mayor peso corporal [75 (66-88) kg vs. 72 (63-82,3) kg, P = 0,002]. El 56% de los pacientes tena esteatosis heptica y el 54,4% presentaba MAFLD. Se detectaron ms ACR en el grupo MAFLD (46,4% vs. 27,5% en controles, P < 0,001). MAFLD se asoci significativamente con la presencia de CRA (OR = 2,32; IC 95%: 1,68-3,19, P < 0,0001). No hubo diferencias respecto de la histologa de los ACR segn la presencia de MAFLD. Conclusin: MAFLD se asocia con un mayor riesgo de ACR. Financiado Fondecyt #1191145 a M.A.,
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.012 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".