Influence of the Fractional CO2 Laser on Immunohistochemical Expression of Smooth Muscle actin in Keloid and Hypertrophic Scars
Bibliographic record
Abstract
Background: Wound healing is a set of elaborate and complex mechanisms including period of oscillation of inflammation, granulation tissue production, and tissue remodeling, which culminates in the restoration of tissue structural stability and injury. That study purposed to evaluate clinical and histopathological changes of keloid and hypertrophic scars before and after CO2 laser treatment. Methods: That interventional research was carried out on individuals with keloids and hypertrophic scars attending the Out-patient Clinic of Dermatology in Hospital of Benha University. Participants were exposed to historical analysis, Local Dermatological inspection, Tissue biopsy, Treatment course by fractional CO2 laser, follow up after treatment. Results: A statistically critical decrease in size of the lesion when comparing among pretreatment and post-treatment [p < 0.05]. Vancouver scale score results were considerably higher pre-treatment than post-treatment [P<0.05]. Conclusion:From the previous results we can conclude that Fractional CO2 laser is a viable therapy option for keloid and hypertrophic scars since it reduces clinical signs such as colour, thickness, and pruritus in addition to improvement at the cellular level.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".