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Record W4327859608 · doi:10.21203/rs.3.rs-2692197/v1

Neurobiological and psychological impact of acute war stress on Ukrainian refugees

2023· preprint· en· W4327859608 on OpenAlexaboutno aff
Ivan Rektor, Monika Fnaskova, Sofia Berezka, Martin Gajdoš, Pavel Říha, Tetyana Evmenova, Marek Preiss

Bibliographic record

VenueResearch Square · 2023
Typepreprint
Languageen
FieldPsychology
TopicPosttraumatic Stress Disorder Research
Canadian institutionsnot available
FundersMasarykova UniverzitaMinisterstvo Školství, Mládeže a Tělovýchovy
KeywordsAnxietyPsychologyInsulaAudiologyStressorParahippocampal gyrusDepression (economics)Clinical psychologyPsychiatryMedicineNeuroscienceTemporal lobe

Abstract

fetched live from OpenAlex

Abstract Based on our research on the impact of extreme stress on Holocaust survivors, we questioned whether the neurobiological and psychological impact of stress could be observed during an ongoing war. We investigated Ukrainian refugee women (UG, n=43) who had been living in the Czech Republic for 2 to 6 months and compared to control group (n=20). Psychological testing: level of posttraumatic stress, Zung Self-Rating Depression Scale, Anxiety Inventory, Intellectual Potential, and Digit Span Wechsler-III. MR imaging: voxel-based morphometry, functional MR, seed-based connectivity, and Montreal Imaging Stress Task (MIST). MRI showed enlargement of the posterior and central parts of the thalamus. The thalamus is connected with the frontal orbital gyrus and insula; the MIST revealed an impact on the parahippocampal gyrus. Conclusion: Acute and ongoing war stress had a significant neurobiological impact on refugees from war-torn Ukraine. The UG scored significantly higher in posttraumatic stress, anxiety, and depression. The thalamus modulates activity in the limbic circuitry. Correlations between MRI activation and levels of posttraumatic stress and anxiety were found in the UG. The data show the impact of acute and ongoing war-related stress on psychological features as well as on the cerebral structure and connectivity of stress-related cortical areas.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.337
GPT teacher head0.576
Teacher spread0.240 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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