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Record W4327862133 · doi:10.1101/2023.03.17.23287412

Estimating the importation risk of mpox virus in 2022 to Hong Kong, China

2023· preprint· en· W4327862133 on OpenAlexaboutno aff
Mingda Xu, Songwei Shan, Zengyang Shao, Yuan Bai, Zhanwei Du, Zhen Wang, Chao Gao

Bibliographic record

VenuemedRxiv · 2023
Typepreprint
Languageen
FieldImmunology and Microbiology
TopicPoxvirus research and outbreaks
Canadian institutionsnot available
FundersNational Natural Science Foundation of China
KeywordsChinaAir travelGeographyPublic healthAviationGlobeInternational airportRisk factorEnvironmental healthRisk assessmentHealth riskSocioeconomicsDemographyBusinessMedicineCartographyEconomicsEngineering

Abstract

fetched live from OpenAlex

Abstract International air travel has been recognized as a crucial factor in the cross-regional transmission of monkeypox (now known as mpox) since this disease rapidly spread across the globe in May 2022. On September 6, 2022, Hong Kong SAR (HK) reported its first imported mpox case with travel history of the United States (US), Canada, and the Philippines. In this study, we estimated the importation risk to HK from 25 international departures from May 1 to September 6, 2022, based on the prevalence of pre-symptomatic mpox cases in the study regions, and time-varying flight mobility evaluated by aggregating multiple open-access air travel datasets (e.g., OpenSky, Aviation Edge). The result indicated that the US had the most significant importation risk of 0.63 (95% CI: 0.32, 0.95) during the study period, followed by the United Kingdom (UK) and Canada with a risk of 0.29 (95% CI: 0.10, 0.63) and 0.17 (95% CI: 0.08, 0.32), respectively. Our study demonstrated that the importation risk of mpox from the US and Canada was substantially higher than other regions, which was aligned with the travel history of the first reported case in HK. Our study provided a simplified computational method for estimating the importation risk of mpox virus based on air travel mobility and disease prevalence. Estimating the international importation risk of mpox is essential for appropriately designing and timely adjusting emergency public health strategies and inbound measures.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.284
Threshold uncertainty score0.564

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.305
Teacher spread0.281 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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