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Record W4360990576 · doi:10.1016/j.eclinm.2023.101886

MASCC clinical practice guidelines for the prevention and management of acute radiation dermatitis: part 1) systematic review

2023· review· en· W4360990576 on OpenAlexaff
Tara Behroozian, Daniel Goldshtein, Julie Ryan Wolf, Corina van den Hurk, Samuel Finkelstein, Henry Lam, Partha Patel, Lauren Kanee, Shing Fung Lee, Adrian Wai Chan, Henry C. Y. Wong, Saverio Caini, Simran Mahal, Samantha Kennedy, Edward Chow, Pierluigi Bonomo

Bibliographic record

VenueEClinicalMedicine · 2023
Typereview
Languageen
FieldMedicine
TopicEffects of Radiation Exposure
Canadian institutionsUniversity of TorontoUniversity of OttawaUniversity of WaterlooSunnybrook Health Science CentreHealth Sciences CentreQueen's UniversityMcMaster University
Fundersnot available
KeywordsMedicineClinical PracticeSystematic reviewIntensive care medicineDermatologyMedical physicsMEDLINEFamily medicine

Abstract

fetched live from OpenAlex

Acute radiation dermatitis (ARD) commonly develops in cancer patients undergoing radiotherapy and is often characterized by erythema, desquamation, and pain. A systematic review was conducted to summarize the current evidence on interventions for the prevention and management of ARD. Databases were searched from 1946 to September 2020 to identify all original studies that evaluated an intervention for the prevention or management of ARD, with an updated search conducted in January 2023. A total of 235 original studies were included in this review, including 149 randomized controlled trials (RCTs). Most interventions could not be recommended due to a low quality of evidence, lack of supporting evidence, or conflicting findings across multiple trials. Photobiomodulation therapy, Mepitel® film, mometasone furoate, betamethasone, olive oil, and oral enzyme mixtures showed promising results across multiple RCTs. Recommendations could not be made solely based on the published evidence due to limited high-quality evidence. As such, Delphi consensus recommendations will be reported in a separate publication.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.024
metaresearch head score (Gemma)0.075
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.026
Threshold uncertainty score0.127

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0240.075
Meta-epidemiology (narrow)0.0030.002
Meta-epidemiology (broad)0.0090.013
Bibliometrics0.0200.016
Science and technology studies0.0010.001
Scholarly communication0.0040.004
Open science0.0050.004
Research integrity0.0050.002
Insufficient payload (model declined to judge)0.0260.007

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.227
GPT teacher head0.559
Teacher spread0.332 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations84
Published2023
Admission routes1
Has abstractyes

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Same venueEClinicalMedicineSame topicEffects of Radiation ExposureFrench-language works237,207