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Record W4361018618 · doi:10.1093/pch/pxad004

An infant with refusal to weight bear and pancytopenia

2023· article· en· W4361018618 on OpenAlexaff
Amira Balbaa, Alexandra Hudson, Alyssa Archibald, Karen Forbes

Bibliographic record

VenuePaediatrics & Child Health · 2023
Typearticle
Languageen
FieldMedicine
TopicParvovirus B19 Infection Studies
Canadian institutionsUniversity of Alberta HospitalUniversity of Alberta
Fundersnot available
KeywordsMedicineLibrary sciencePancytopeniaFamily medicinePediatricsGerontologyHistoryPathology

Abstract

fetched live from OpenAlex

A 13-month-old male presented to the Emergency Department with bilateral leg bruising and refusal to stand that had progressed over a 2-month period. There was associated fatigue, pallor, and estimated 1 kg weight loss over this time. He demonstrated oral aversion to solids and was almost exclusively breastfed. This was thought to be secondary to a mild caustic injury due to toilet bowl cleaner ingestion at 8 months of age. Family history was unremarkable. Physical exam revealed tachycardia, mild hepatosplenomegaly, and an enlarged posterior auricular lymph node. Blood work 1-month prior demonstrated normocytic anemia (Hb 98 g/L, mean corpuscular volume 88 fL). Repeat blood work on presentation revealed progression to pancytopenia, with macrocytic anemia (Hb 61 g/L, MCV 100 fL), mild lymphopenia (3.7 10*9/L), and thrombocytopenia (116 10*9/L). Blasts were noted on peripheral smear (absolute 0.4, <5%). Lactate dehydrogenase was elevated (2,171 U/L) and Epstein-Barr virus and cytomegalovirus serologies were negative.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.074
Threshold uncertainty score0.671

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.320
Teacher spread0.302 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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