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Record W4362455067 · doi:10.3171/2023.1.focus22641

Introduction. Adult hydrocephalus: advancements in diagnosis, treatment, and patient outcomes

2023· article· en· W4362455067 on OpenAlexaff
Mark G. Hamilton, Hanna Israelsson, Giorgio Palandri, Benjamin D. Elder, Michael A. Williams

Bibliographic record

VenueNeurosurgical FOCUS · 2023
Typearticle
Languageen
FieldNeuroscience
TopicCerebrospinal fluid and hydrocephalus
Canadian institutionsUniversity of Calgary
Fundersnot available
KeywordsHydrocephalusMedicineIntensive care medicineSurgery

Abstract

fetched live from OpenAlex

HydrocepHalus in adults comprises a diverse grouping of etiologies, pathophysiology, diagnostic criteria, and treatment needs.Furthermore, hydrocephalus is more common in adults than in children, 1 and surgical procedures for hydrocephalus in adults in the US are annually performed almost five times more frequently compared with pediatric patients. 2A previously described pragmatic, clinically oriented organizational scheme helps to ensure we distinguish four types of patients within the spectrum of adult hydrocephalus: 1) transitional patients (previously diagnosed with hydrocephalus and treated as children), 2) patients with previously unrecognized congenital hydrocephalus, 3) patients with acquired hydrocephalus with an identifiable etiology (e.g., subarachnoid hemorrhage, cerebral trauma, or infection), and 4) patients with suspected or proven idiopathic normal pressure hydrocephalus. 3 There are distinct differences in these four patient groupings regarding diagnostic, treatment, and outcome issues.This is the third issue of Neurosurgical Focus since 2007 devoted to adult hydrocephalus, with the current emphasis on advancements in diagnosis, treatment, and patient outcomes.This issue provides an excellent overview of these essential topics.Two crucial messages can be identified.The first is that while treatment for adult hydrocephalus patients with CSF shunts is common, failure rates, despite being poorly reported, are significant, with shunt obstruction and infection remaining substantial issues to overcome.We need to standardize the mode and quality of said data to allow a better understanding of shunt failure-related issues.The second message is that efforts to enhance our ability to select adult patients with hydrocephalus who will benefit from treatment with shunt surgery are improving.Consequently, it is no longer sufficient to report outcomes only in terms of surgical technical success or complications.Instead, as shown in this issue, clinical hydrocephalus studies should, when possible, include patient-relevant and patient-centered measures such as cognition, mobility, urinary control, and quality of life.We hope that this issue will inspire readers to attend as much to the functional outcomes as they do to the surgical outcomes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.594
Threshold uncertainty score0.921

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.276
Teacher spread0.256 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2023
Admission routes1
Has abstractyes

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