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Record W4362505920 · doi:10.1128/mbio.00464-23

<i>Rothia</i> from the Human Nose Inhibit <i>Moraxella catarrhalis</i> Colonization with a Secreted Peptidoglycan Endopeptidase

2023· article· en· W4362505920 on OpenAlexaff
Reed M. Stubbendieck, Eishika Dissanayake, Peter M. Burnham, Susan Zelasko, Mia I. Temkin, Sydney S. Wisdorf, Rose F. Vrtis, James E. Gern, Cameron R. Currie

Bibliographic record

VenuemBio · 2023
Typearticle
Languageen
FieldMedicine
TopicMycobacterium research and diagnosis
Canadian institutionsMcMaster University
FundersNational Center for Advancing Translational SciencesU.S. National Library of MedicineNational Institute of General Medical SciencesTexas State UniversityNational Institutes of HealthOklahoma State UniversityUniversity of Wisconsin-MadisonNational Institute of Allergy and Infectious DiseasesDivision of Intramural Research, National Institute of Allergy and Infectious Diseases
KeywordsMoraxella catarrhalisMicrobiologyPeptidoglycanMoraxella (Branhamella) catarrhalisMoraxellaEndopeptidaseColonizationNeisseriaceaeBiologyChemistryBacteriaStreptococcus pneumoniaeEnzymeAntibioticsBiochemistryGenetics

Abstract

fetched live from OpenAlex

Moraxella catarrhalis is a pathobiont of the respiratory tract, responsible for ear infections in children and wheezing illnesses in children and adults with chronic respiratory diseases. Detection of M. catarrhalis during wheezing episodes in early life is associated with the development of persistent asthma.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.114
Threshold uncertainty score0.887

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.278
Teacher spread0.255 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations35
Published2023
Admission routes1
Has abstractyes

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