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Record W4362532766 · doi:10.1186/s12888-023-04605-2

Determinants of effective treatment coverage for posttraumatic stress disorder: findings from the World Mental Health Surveys

2023· article· en· W4362532766 on OpenAlexaff
Dan J. Stein, Alan E. Kazdin, Richard J. Munthali, Irving Hwang, Meredith Harris, Jordi Alonso, Laura Helena Andrade, Ronny Bruffaerts, Graça Cardoso, Stephanie Chardoul, Giovanni de Girolamo, Silvia Florescu, Oye Gureje, Josep María Haro, Aimée Karam, Elie G. Karam, Viviane Kovess–Masféty, Sing Lee, María Elena Medina‐Mora, Fernando Navarro‐Mateu, José Posada‐Villa, Juan Carlos Stagnaro, Margreet ten Have, Nancy A. Sampson, Ronald C. Kessler, Daniel Vigo, Sergio Aguilar‐Gaxiola, Yasmin Altwaijri, Lukoye Atwoli, Corina Benjet, Guilherme Borges, Evelyn J. Bromet, Brendan Bunting, José Miguel Caldas‐de‐Almeida, Somnath Chatterji, Louisa Degenhardt, Koen Demyttenaere, Hristo Hinkov, Chiyi Hu, Peter de Jonge, Georges Karam, Norito Kawakami, Andrzej Kiejna, Jean‐Pierre Lépine, John J. McGrath, Jacek Moskalewicz, Marina Piazza, Kate M. Scott, Tim Slade, Yolanda Torres, María Carmen Viana, Harvey Whiteford, David R. Williams, Bogdan Wojtyniak

Bibliographic record

VenueBMC Psychiatry · 2023
Typearticle
Languageen
FieldPsychology
TopicPosttraumatic Stress Disorder Research
Canadian institutionsUniversity of British Columbia
FundersNational Institute on Drug AbuseNational Institute of Mental HealthConsejería de Sanidad y Política Social, Comunidad Autónoma de la Región de MurciaInstituto de Salud Carlos IIIFundação para a Ciência e a TecnologiaMedical Research CouncilPan American Health OrganizationRegione PiemonteBristol-Myers SquibbServicio Murciano de SaludServierMinisterio de Salud de la NaciónMinisterio de Ciencia y TecnologíaJohn W. Alden TrustUniversidade de LisboaFogarty International CenterBundesministerium für GesundheitGeneralitat de CatalunyaPfizer FoundationAstraZenecaFundação de Amparo à Pesquisa do Estado de São PauloH. Lundbeck A/SSubstance Abuse and Mental Health Services AdministrationSouth African Medical Research CouncilFundação ChampalimaudFundación para la Formación e Investigación Sanitarias de la Región de MurciaEuropean CommissionWorld Health OrganizationGlaxoSmithKlineU.S. Public Health ServiceJohn D. and Catherine T. MacArthur FoundationEli Lilly and CompanyPfizerUniversidad CESRobert Wood Johnson Foundation
KeywordsPharmacotherapyMental healthMedicinePsychiatryMental health servicePosttraumatic stress

Abstract

fetched live from OpenAlex

BACKGROUND: Posttraumatic stress disorder (PTSD) is associated with significant morbidity, but efficacious pharmacotherapy and psychotherapy are available. Data from the World Mental Health Surveys were used to investigate extent and predictors of treatment coverage for PTSD in high-income countries (HICs) as well as in low- and middle-income countries (LMICs). METHODS: Seventeen surveys were conducted across 15 countries (9 HICs, 6 LMICs) by the World Health Organization (WHO) World Mental Health Surveys. Of 35,012 respondents, 914 met DSM-IV criteria for 12-month PTSD. Components of treatment coverage analyzed were: (a) any mental health service utilization; (b) adequate pharmacotherapy; (c) adequate psychotherapy; and (d) effective treatment coverage. Regression models investigated predictors of treatment coverage. RESULTS: 12-month PTSD prevalence in trauma exposed individuals was 1.49 (S.E., 0.08). A total of 43.0% (S.E., 2.2) received any mental health services, with fewer receiving adequate pharmacotherapy (13.5%), adequate psychotherapy (17.2%), or effective treatment coverage (14.4%), and with all components of treatment coverage lower in LMICs than HICs. In a multivariable model having insurance (OR = 2.31, 95 CI 1.17, 4.57) and severity of symptoms (OR = .35, 95% CI 0.18, 0.70) were predictive of effective treatment coverage. CONCLUSION: There is a clear need to improve pharmacotherapy and psychotherapy coverage for PTSD, particularly in those with mild symptoms, and especially in LMICs. Universal health care insurance can be expected to increase effective treatment coverage and therefore improve outcomes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.062
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.060
GPT teacher head0.405
Teacher spread0.345 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations28
Published2023
Admission routes1
Has abstractyes

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