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Evidence-based consensus guidelines for the management of catatonia: Recommendations from the British Association for Psychopharmacology

2023· article· en· 213 citations· W4364354368 on OpenAlex· 10.1177/02698811231158232

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.
Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

Full frame distilled prediction

Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

Candidate categories
none
Consensus categories
none
Domain
Candidate signal: noneConsensus signal: none
Study design
Candidate signal: Not applicableConsensus signal: Not applicable
Genre
Candidate signal: EmpiricalConsensus signal: none
Teacher disagreement score
0.535
Threshold uncertainty score
0.410
Validation status
machine_predicted_unvalidated · codex-gemma-dda1882f352a

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.147
GPT teacher head0.464
Teacher spread
0.317 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

The British Association for Psychopharmacology developed an evidence-based consensus guideline on the management of catatonia. A group of international experts from a wide range of disciplines was assembled. Evidence was gathered from existing systematic reviews and the primary literature. Recommendations were made on the basis of this evidence and were graded in terms of their strength. The guideline initially covers the diagnosis, aetiology, clinical features and descriptive epidemiology of catatonia. Clinical assessments, including history, physical examination and investigations are then considered. Treatment with benzodiazepines, electroconvulsive therapy and other pharmacological and neuromodulatory therapies is covered. Special regard is given to periodic catatonia, malignant catatonia, neuroleptic malignant syndrome and antipsychotic-induced catatonia. There is attention to the needs of particular groups, namely children and adolescents, older adults, women in the perinatal period, people with autism spectrum disorder and those with certain medical conditions. Clinical trials were uncommon, and the recommendations in this guideline are mainly informed by small observational studies, case series and case reports, which highlights the need for randomised controlled trials and prospective cohort studies in this area.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

The record

Venue
Journal of Psychopharmacology
Topic
Electroconvulsive Therapy Studies
Field
Medicine
Canadian institutions
Royal Ottawa Mental Health CentreUniversity of Ottawa
Funders
Janssen PharmaceuticalsNational Institute of Mental HealthNational Institute on AgingMedical Research CouncilOffice of Rural HealthUCLH Biomedical Research CentreHorizon 2020 Framework ProgrammeVGH and UBC Hospital FoundationDeutsche ForschungsgemeinschaftUniversity College LondonWisconsin Economic Development CorporationNational Institute for Health and Care ResearchCanadian Institutes of Health ResearchBritish Medical AssociationRoyal College of Physicians of EdinburghWellcome TrustStanley Medical Research InstituteMichael Smith Health Research BCNational Alliance for Research on Schizophrenia and DepressionNational Institutes of Health
Keywords
CatatoniaGuidelinePsychiatryObservational studyElectroconvulsive therapyMedicinePsychologyClinical trialAutismNeuroleptic malignant syndromeEtiologyPsychopharmacologyClinical psychologyPediatricsSchizophrenia (object-oriented programming)Pathology
Has abstract in OpenAlex
yes