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Record W4364375650 · doi:10.1016/j.labinv.2023.100147

Associations Among Antiphospholipid Antibody Types, Isotypes, and Titers: An AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking (APS ACTION) Study

2023· article· en· W4364375650 on OpenAlex
Elena Gkrouzman, Rohan Willis, Danieli Andrade, Maria G. Tektonidou, Vittorio Pengo, Guillermo Ruiz‐Irastorza, H. Michael Belmont, Paul R. Fortin, Maria Gerosa, Flávio Signorelli, Tatsuya Atsumi, D. Ware Branch, Cecilia Nalli, Esther Rodríguez-Almaraz, Michelle Petri, Ricard Cervera, Jason S. Knight, Maria Efthymiou, Hannah Cohen, María Laura Bertolaccini, Doruk Erkan, Robert Roubey, Guillermo Pons‐Estel, Bill Giannakopoulos, Steve Krilis, Guilherme Ramires de Jesús, Roger A. Levy, Gustavo Guimarães Moreira Balbi, Ann E. Clarke, Leslie Skeith, Lanlan Ji, Zhouli Zhang, Chengde Yang, Hui Shi, Stéphane Zuily, Denis Wahl, Laura Andréoli, Anǵela Tincani, Cecilia Beatrice Chighizola, Pier Luigi Meroni, Chun‐Yan Cheng, Giulia Pazzola, Savino Sciascia, Silvia Foddai, Massimo Radin, Stacy Davis, Olga Amengual, Imad Uthman, Maarten Limper, Philip de Groot, Amaia Ugarte, Ignasi Rodríguez‐Pintó, José Pardos‐Gea, María José Cuadrado, M. Á. Aguirre, C. López-Pedrera, Bahar Artım-Esen, Murat İnanç, Munther A. Khamashta, Ian Mackie, Giovanni Sanna, Yu Zuo, Rebecca Karp Leaf, Thomas L. Ortel, Nina Kello, Steven R. Levine, Jacob H. Rand, Medha Barbhaiya, Jane E. Salmon, Michael D. Lockshin, Ali A. Duarte Garcia

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueLaboratory Investigation · 2023
Typearticle
Languageen
FieldMedicine
TopicSystemic Lupus Erythematosus Research
Canadian institutionsUniversité Laval
FundersNational Institutes of HealthClinical and Translational Science Center, Weill Cornell Medical CollegeNational Institute of Arthritis and Musculoskeletal and Skin DiseasesWeill Cornell Medical CollegeJohns Hopkins University
KeywordsAntiphospholipid syndromeLupus anticoagulantMedicineImmunologyInternal medicineAntibodyOdds ratioTiterProspective cohort study

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.007
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.010
Threshold uncertainty score0.799

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0070.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.257
GPT teacher head0.490
Teacher spread0.233 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it