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Record W4365146139 · doi:10.5489/cuaj.8223

Dorsal shortening vs. ventral lengthening procedure for correction of congenital ventral curvature in patients with and without severe hypospadias

2023· review· en· W4365146139 on OpenAlexaffvenue
Michael Chua, Priyank Yadav, Adam Bobrowski, Jin K. Kim, Jan Michael Silangcruz, Jessica M. Ming, Mandy Rickard, Armando J. Lorenzo, Darius Bägli, Antoine E. Khoury

Bibliographic record

VenueCanadian Urological Association Journal · 2023
Typereview
Languageen
FieldMedicine
TopicUrological Disorders and Treatments
Canadian institutionsSickKids FoundationCentre for Global Health ResearchHospital for Sick ChildrenUniversity of Toronto
Fundersnot available
KeywordsHypospadiasDorsumAnatomyCurvatureMedicineMathematicsGeometry

Abstract

fetched live from OpenAlex

Introduction: Debates remain on the ideal congenital ventral curvature correction among patients with and without severe hypospadias. Herein, we aimed to assess the comparative surgical outcome of dorsal shortening (DS) vs. ventral lengthening (VL) procedures for correcting congenital ventral curvatures. Method: A systematic literature search was performed in September 2021 using the PubMed, EMBASE, Scopus, CENTRAL, ProQuest, and Clinicaltrials.gov databases. Comparative studies were identified and evaluated according to Cochrane Collaboration recommendations. Assessed outcomes included success and complication rates, which were extrapolated for the respective odds ratios (OR) with 95% confidence intervals (CIs). Subgroup analyses were performed according to congenital curvature, with or without severe hypospadias or recurrent curvatures (International Prospective Register of Systematic Reviews (PROSPERO): CRD42021276193). Results: Based on pooled effect estimates from 12 studies with 430 (DS 253, VL 177) cases of ventral curvature repair, VL was able to render a better success rate for curvature correction (OR 4.20, 95% CI 2.11, 8.33) than DS repair, with comparable composite surgical complication rates (OR 0.77, 95% CI 0.27, 2.18). Furthermore, subgroup analysis showed that the success rate remained significantly better for the VL approach among patients with associated severe hypospadias (OR 3.59, 95% CI 1.25, 10.26) and recurrent penile curvatures (OR 5.70, 95% CI 1.69, 19.21), but not among those with congenital curvature without hypospadias or those with mild hypospadias (OR 2.99, 95% CI 0.32, 27.57). Conclusions: In correcting congenital curvature associated with severe hypospadias and recurrent curvatures, VL procedures might render a modestly better success rate; however, careful selection of appropriate patients seems to be the crucial key to the best outcome. The surgical complication rate seems to be comparable between the two approaches.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.253
Threshold uncertainty score0.893

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.261
Teacher spread0.240 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2023
Admission routes2
Has abstractyes

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