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Record W4365459023 · doi:10.1002/sim.9727

Causal inference with longitudinal data subject to irregular assessment times

2023· article· en· W4365459023 on OpenAlexafffund
Eleanor Pullenayegum, Catherine S. Birken, Jonathon L. Maguire

Bibliographic record

VenueStatistics in Medicine · 2023
Typearticle
Languageen
FieldMathematics
TopicAdvanced Causal Inference Techniques
Canadian institutionsSt. Michael's HospitalInstitute for Clinical Evaluative SciencesUniversity of TorontoSickKids FoundationHospital for Sick ChildrenPublic Health Ontario
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsCausal inferenceInferenceSubject (documents)Computer scienceLongitudinal dataStatisticsEconometricsStatistical inferenceArtificial intelligenceMathematicsData mining

Abstract

fetched live from OpenAlex

Data collected in the context of usual care present a rich source of longitudinal data for research, but often require analyses that simultaneously enable causal inferences from observational data while handling irregular and informative assessment times. An inverse-weighting approach to this was recently proposed, and handles the case where the assessment times are at random (ie, conditionally independent of the outcome process given the observed history). In this paper, we extend the inverse-weighting approach to handle a special case of assessment not at random, where assessment and outcome processes are conditionally independent given past observed covariates and random effects. We use multiple outputation to accomplish the same purpose as inverse-weighting, and apply it to the Liang semi-parametric joint model. Moreover, we develop an alternative joint model that does not require covariates for the outcome model to be known at times where there is no assessment of the outcome. We examine the performance of these methods through simulation and illustrate them through a study of the causal effect of wheezing on time spent playing outdoors among children aged 2-9 years and enrolled in the TargetKids! study.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.275
Threshold uncertainty score0.762

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.219
GPT teacher head0.510
Teacher spread0.291 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2023
Admission routes2
Has abstractyes

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