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Record W4365788237 · doi:10.2737/fpl-rn-422

Gas chromatography–mass spectrometry analysis of Alaska yellow-cedar extractive components.

2023· report· en· W4365788237 on OpenAlexaboutno aff
Phoebe Wagner, Gabriel L. Epstein, Brett Hinkforth, Doreen Mann, Roderquita Moore

Bibliographic record

Venuenot available
Typereport
Languageen
FieldMedicine
TopicCholinesterase and Neurodegenerative Diseases
Canadian institutionsnot available
Fundersnot available
KeywordsMass spectrometryChromatographyGas chromatography–mass spectrometryChemistryGas chromatographyEnvironmental scienceEnvironmental chemistry

Abstract

fetched live from OpenAlex

Alaska yellow-cedar (Cupressus nootkatensis) is a softwood tree species native to the Pacific coast of Canada and is known to contain various biologically active extractive components.Extractives are nonstructural chemical compounds found within wood that are primarily responsible for the durability of the tree itself and can, in some species, fend off attacks from microbes, insects, and other agents.Durability in wood often translates to biological activity in the human body, and some extractive compounds have already been identified as being biologically active.Extractives of Alaska yellow-cedar were separated using liquid-liquid fractionation and were identified using gas chromatography-mass spectroscopy (GC-MS).Vial B solvent mixture polarity separated 50% of the sample and had more compounds identified than the other fractions.The separated samples in vials F and G each had only one compound identified, and vial H had no compounds identified.Multiple compounds were identified in the other fractions that exhibit biological activity, such as carvacrol, nootkatone, α-cadinol, androsta-1,4,6-trien-3one,17-hydroxy-(17β), and falcarinol.Further investigation on the vials with one or less compounds will be analyzed using instrumentation with more sensitivity and resolving power to identified trace compounds.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.014
Threshold uncertainty score0.029

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0020.001
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.092
GPT teacher head0.370
Teacher spread0.278 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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