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Preliminary evaluation of in vitro anti-urolithiasic effect of six Algerian plant products

2023· article· en· W4366492465 on OpenAlexvenueno aff
Salem Benamara, Malika Chekroune

Bibliographic record

VenueDiscovery Phytomedicine - Journal of Natural Products Research and Ethnopharmacology · 2023
Typearticle
Languageen
FieldMedicine
TopicKidney Stones and Urolithiasis Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsDistilled waterChemistryFood scienceCalcium oxalateOrange (colour)SodiumLemon juiceSolanumCitrus × sinensisAqueous solutionCalciumHorticultureChromatographyBiologyOrganic chemistry

Abstract

fetched live from OpenAlex

The present paper reports on the preliminary evaluation of in vitro anti-urolithiasic effect (AULE) of six Algerian plant products: lemon (Citrus limon L.), orange (Citrus sinensis L.), grapefruit (Citrus grandis L.), lemon/grapefruit (1/1 ratio, v/v) and tomato (Solanum lycopersicum L.) juices, [and aqueous extract from hairy rupturewort (Herniaria hirsuta L.), the bi-distilled water being taken as reference. The AULE was evaluated, based on the ability of considered plant liquids to prevent the crystallization of calcium oxalate (CaOx) from the mixture of stock solutions of calcium chloride and sodium oxalate. For this, the juices and the aqueous extract to be analyzed were used as solvents to prepare the two stock solutions. The formation of CaOx was assessed by means of microscopic observation and presented in the form of images. A better AULE was observed for citrus juices, compared with bi-distilled water, tomato juice and hairy rupturewort extract. In the case of lemon juice, it was also found that the AULE is more effective when the juice acidity is adjusted to high pH values (6-7). Based on these results, citrus juices may be recommended for the prevention of urinary lithiogenesis. However, in-depth confirmatory studies are always desired, knowing that opinions are not unanimous on this issue.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.064
GPT teacher head0.418
Teacher spread0.353 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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Same venueDiscovery Phytomedicine - Journal of Natural Products Research and EthnopharmacologySame topicKidney Stones and Urolithiasis TreatmentsFrench-language works237,207