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Record W4367595694 · doi:10.1101/2023.05.01.538918

High pathogenicity avian influenza (H5N1) in Northern Gannets: Global spread, clinical signs, and demographic consequences

2023· preprint· en· W4367595694 on OpenAlexafffundabout
Jude V. Lane, Jana W. E. Jeglinski, Stephanie Avery‐Gomm, Elmar Ballstaedt, Ashley C. Banyard, Tatsiana Barychka, Ian H. Brown, Brigitte Brugger, Tori V. Burt, Noah G. Careen, Johan H Funder Castenschiold, Signe Christensen‐Dalsgaard, Shannon Clifford, Sydney M. Collins, Emma J. A. Cunningham, Jóhannis Danielsen, Francis Daunt, Kyle J. N. d’Entremont, Parker Doiron, Steven Duffy, Matthew D. English, Marco Falchieri, Jolene A. Giacinti, Britt Gjerset, Silje Granstad, David Grémillet, Magella Guillemette, Gunnar Þór Hallgrímsson, Keith C. Hamer, Sjúrður Hammer, Katherine Harrison, Justin D Hart, Ciaran Hatsell, Richard Humpidge, Joe James, Audrey Jenkinson, Mark Jessopp, Megan Jones, Stéphane Lair, Tom Lewis, Alexandra A. Malinowska, Aly McCluskie, Gretchen McPhail, Børge Moe, William A. Montevecchi, Greg Morgan, Caroline Nichol, Craig Nisbet, Bergur Olsen, Jennifer F. Provencher, Pascal Provost, Alex Purdie, Jean‐François Rail, Gregory J. Robertson, Yannick Seyer, Maggie Sheddan, Catherine Soos, Nia Stephens, Hallvard Strøm, Vilhjálmur Svansson, T. David Tierney, Glen Tyler, Tom Wade, Sarah Wanless, Christopher R. E. Ward, Sabina I. Wilhelm, Saskia Wischnewski, Lucy J. Wright, Bernie Zonfrillo, Jason Matthiopoulos, Stephen C. Votier

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2023
Typepreprint
Languageen
FieldMedicine
TopicInfluenza Virus Research Studies
Canadian institutionsUniversité de MontréalUniversity of Prince Edward IslandMemorial University of NewfoundlandUniversité du Québec à RimouskiEnvironment and Climate Change Canada
FundersNatural Environment Research CouncilBiotechnology and Biological Sciences Research CouncilFisheries and Oceans CanadaDirectorate for Biological SciencesScotland’s Rural CollegeNatural Sciences and Engineering Research Council of CanadaUniversity of EdinburghSight Research UKDepartment for Environment, Food and Rural Affairs, UK Government
KeywordsOutbreakInfluenza A virus subtype H5N1BiologyPopulationSerologyWaterfowlSeabirdGeographyZoologyEcologyDemographyVirusVirologyHabitatPredationAntibodyImmunology

Abstract

fetched live from OpenAlex

Abstract During 2021-22 High Pathogenicity Avian Influenza (HPAI) killed thousands of wild birds across Europe and North America, suggesting a change in infection dynamics and a shift to new hosts, including seabirds. Northern Gannets ( Morus bassanus ) appeared especially severely impacted, but limited understanding of how the virus spread across the metapopulation, or the demographic consequences of mass mortality limit our understanding of its severity. Accordingly, we collate information on HPAIV outbreaks across most North Atlantic gannet colonies and for the largest colony (Bass Rock, UK), provide impacts on population size, breeding success, adult survival, and preliminary results on serology. Unusually high numbers of dead gannets were first noted in Iceland during April 2022. Outbreaks in May occurred in many Scottish colonies, followed by colonies in Canada, Germany and Norway. By the end of June, outbreaks had occurred in five Canadian colonies and in the Channel Islands. Outbreaks in 12 UK and Ireland colonies appeared to follow a clockwise pattern with the last infected colonies recorded in late August/September. Unusually high mortality was recorded at 40 colonies (75% of global total colonies). Dead birds testing positive for HPAIV H5N1 were associated with 58% of these colonies. At Bass Rock, the number of occupied sites decreased by at least 71%, breeding success declined by ∼66% compared to the long-term UK mean and adult survival between 2021 and 2022 was 42% lower than the preceding 10-year average. Serological investigation detected antibodies specific to H5 in apparently healthy birds indicating that some gannets recover from HPAIV infection. Further, most of these recovered birds had black irises, suggestive of a phenotypic indicator of previous infection. Untangling the impacts of HPAIV infection from other key pressures faced by seabirds is key to establishing effective conservation strategies for threatened seabird populations, HPAIV being a novel and pandemic threat.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.019
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.003
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0010.001
Science and technology studies0.0000.002
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.077
GPT teacher head0.346
Teacher spread0.269 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations18
Published2023
Admission routes3
Has abstractyes

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