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Record W4375844710 · doi:10.1111/apa.16815

Searching for evidence in neonatology

2023· review· en· W4375844710 on OpenAlexaff
Ola Didrik Saugstad, Haresh Kirpalani

Bibliographic record

VenueActa Paediatrica · 2023
Typereview
Languageen
FieldMedicine
TopicNeonatal Respiratory Health Research
Canadian institutionsMcMaster University
Fundersnot available
KeywordsMedicineIntuitionHindsight biasRandomized controlled trialOutcome (game theory)MEDLINESelection biasEvidence-based medicineClinical trialAlternative medicineCognitive psychologySurgeryPathologyPsychology

Abstract

fetched live from OpenAlex

Evidence-based medicine has changed clinical practice by incorporating data from randomised controlled trials (RCTs). While some biases in RCTs are well recognised, we discuss some less acknowledged. Selection bias may arise in the consent stage. Industry-funded studies more often report a positive outcome. Post-hoc changes of outcome measures and other mis-reporting lowers the reliability of outcome data. Finally, even the GRADE system retains subjectivity. CONCLUSION: Moving from "intuition" into "evidence-based" medicine involves grappling with several pitfalls. These pose challenges for authors, editors, reviewers, and readers. All require vigilance before drawing conclusions from presented data.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.041
metaresearch head score (Gemma)0.183
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.959
Threshold uncertainty score0.218

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0410.183
Meta-epidemiology (narrow)0.0020.002
Meta-epidemiology (broad)0.0100.005
Bibliometrics0.0210.017
Science and technology studies0.0010.003
Scholarly communication0.0100.008
Open science0.0040.005
Research integrity0.0080.006
Insufficient payload (model declined to judge)0.0140.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.383
GPT teacher head0.530
Teacher spread0.148 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
DomainMethods
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations9
Published2023
Admission routes1
Has abstractyes

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