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Record W4377695790 · doi:10.1016/s1474-4422(23)00131-x

Neuroimaging standards for research into small vessel disease—advances since 2013

2023· review· en· W4377695790 on OpenAlexafffund
Marco Duering, Geert Jan Biessels, Amy Brodtmann, Christopher Chen, Charlotte Cordonnier, Frank‐Erik de Leeuw, Stéphanie Debette, Richard Frayne, Éric Jouvent, Natalia S. Rost, Annemieke ter Telgte, Rustam Al‐Shahi Salman, Walter H. Backes, Hee‐Joon Bae, Rosalind Brown, Hugues Chabriat, Alberto De Luca, Charles DeCarli, Anna Dewenter, Fergus Doubal, Michael Ewers, Thalia S. Field, Aravind Ganesh, Steven M. Greenberg, Karl G. Helmer, Saima Hilal, Angela C.C. Jochems, Hanna Jokinen, Hugo J. Kuijf, Bonnie Lam, Jessica Lebenberg, Bradley J. MacIntosh, Pauline Maillard, Vincent Mok, Leonardo Pantoni, Salvatore Rudilosso, Claudia L. Satizábal, Markus D. Schirmer, Reinhold Schmidt, Colin Smith, Julie Staals, Michael J. Thrippleton, Susanne J. van Veluw, Prashanthi Vemuri, Yilong Wang, David J. Werring, Marialuisa Zedde, Rufus Akinyemi, Óscar H. Del Brutto, Hugh S. Markus, Yi‐Cheng Zhu, Eric E. Smith, Martin Dichgans, Joanna M. Wardlaw

Bibliographic record

VenueThe Lancet Neurology · 2023
Typereview
Languageen
FieldMedicine
TopicCerebrovascular and Carotid Artery Diseases
Canadian institutionsOntario Brain InstituteUniversity of TorontoSunnybrook Health Science CentreUniversity of British ColumbiaHotchkiss Brain InstituteFoothills Medical CentreUniversity of Calgary
FundersDaiichi Sankyo EuropeMedical Research CouncilCanadian Institutes of Health ResearchBayer KoreaSanofi GenzymeDirectorate for Biological SciencesNational Institutes of HealthDementias Platform UKUK Dementia Research InstituteEuropean Stroke OrganisationEuropean Academy of NeurologyAlberta InnovatesEVER Neuro PharmaAstraZeneca KoreaNovo NordiskEisaiFondation LeducqAgence Nationale de la RechercheBritish Heart FoundationSanofiGovernment of CanadaBayer VitalBristol-Myers SquibbNestlé Health ScienceConsortium canadien en neurodégénérescence associée au vieillissementAmicus TherapeuticsCanadian Cardiovascular SocietyAlzheimer SocietyAlzheimer's SocietyBiotechnology and Biological Sciences Research CouncilWellcome TrustResearch Councils UKYuhanMcMaster UniversityAlexion PharmaceuticalsPfizerBiogenAlnylam PharmaceuticalsHeart and Stroke Foundation of CanadaUK Research and InnovationEli Lilly and CompanyAstraZenecaSiemens HealthineersAmgenWeston Brain InstituteAmerican Heart Association
KeywordsNeuroimagingCognitionDiseaseMedicineNeuroscienceCognitive declineStroke (engine)NeurodegenerationMagnetic resonance imagingPsychologyPathologyRadiologyDementia

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Direct model labels (unvalidated)

Per-model category and study-design labels from the labeling rounds. They are machine output, unvalidated, and the disagreement between models ships as data. No study design here is MEDLINE-validated yet.

Model armCategoriesStudy designConfidence
gemmano category
Domain: not available · Genre: Review
About the Canadian research system: no · About a Canadian topic: no
Not applicablehigh
gptno category
Domain: not available · Genre: Review
About the Canadian research system: no · About a Canadian topic: no
Other designmedium
models splitAgreement compares identical category sets and study designs across arms.

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.007
metaresearch head score (Gemma)0.015
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.007
Threshold uncertainty score0.038

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0070.015
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0040.002
Bibliometrics0.0050.004
Science and technology studies0.0000.002
Scholarly communication0.0030.004
Open science0.0020.002
Research integrity0.0040.005
Insufficient payload (model declined to judge)0.0040.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.196
GPT teacher head0.460
Teacher spread0.264 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Labeled directly by 2 models reading the full record.

The models applied no category: nothing in the taxonomy fit this work.

The models disagree on parts of this classification; every voice is preserved in the section at the end of the page.

Study designNot applicable · Other design
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations973
Published2023
Admission routes2
Has abstractno

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