Bibliographic record
Abstract
BACKGROUND: Treatment options for residual, recurrent, or new primary (ReRuNeR) oropharyngeal cancer (OPC) can result in complex decision making where patients may have to choose potential cure over function.However, little is known about the functional impact of the various treatment modalities.METHODS: A systematic review (2011)(2012)(2013)(2014)(2015)(2016)(2017)(2018)(2019)(2020)(2021) to identify swallowing and quality of life (QoL) outcome tools, and outcomes reported for patients undergoing treatment for ReRuNeR OPC.Ethics not indicated.RESULTS: Of the 2,398 articles identifi ed, 18 studies were eligible for inclusion.Due to the heterogeneity of studies, meta-analysis was not possible.A wide range of swallowing tools (n=6) and QoL tools (n=7), used at various timepoints were identifi ed.Non-surgical trials reported on QoL outcomes alone whereas surgical trials reported unidimensional swallowing outcomes.There is a transient improvement in QoL following palliative treatments, before a gradual deterioration over time.It would appear that there is an initial deterioration in swallowing function in the acute phase post-surgery.However, longer term post-surgical swallowing outcomes remain unclear with some studies reporting return to baseline, whilst others show minimal improvement at 6 months or gradual improvement over time at up to 12 months post-surgery.Functional and QoL outcomes are rarely investigated together.CONCLUSIONS: On a background of previous treatment for head and neck cancer, there is the potential for baseline swallowing diffi culties and change over time with further treatment.There is a need for further research to establish a core dataset of robust and clinically relevant outcome measures for this group of patients.'I feel like I'm drowning': SLT intervention for tracheostomy weaning and severe dysphagia in a patient with COVID-19 and leukaemia Doris O 1 1 UCLH PURPOSE: Single case report of a patient who presented with COVID-19 and new onset of acute myeloid leukaemia, at a specialist haematology centre; requiring SLT intervention for tracheostomy weaning and severe dysphagia.Details shared with consent.BACKGROUND: The patient was intubated for 17 days prior to tracheostomy placement.OME: soft palate asymmetry on the left (CN IX) with hypernasality and a tongue deviation to the right (CN X11).The patient was dysphonic with diplophonia.A FNE was performed; identifying a left vocal cord palsy fi xed in abduction with copious thick secretions silently aspirated.An intense dysphagia
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.003 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".