Temporal imprecision and phase instability in schizophrenia resting state EEG
Why this work is in the frame
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Bibliographic record
Abstract
Schizophrenia is characterized by temporal imprecision and irregularities on neuronal, psychological cognitive, and behavioral levels which are usually tested during task-related activity. This leaves open whether analogous temporal imprecision and irregularities can already be observed in the brain's spontaneous activity as measured during the resting state; this is the goal of our study. Building on recent task-related data, we, using EEG, aimed to investigate the temporal precision and regularity of phase coherence over time in healthy, schizophrenia, and bipolar disorder participants. To this end, we developed a novel methodology, nominal frequency phase stability (NFPS), that allows to measure stability over phase angles in selected frequencies. By applying sample entropy quantification to the time-series of the nominal frequency phase angle time series, we found increased irregularities in theta activity over a frontocentral electrode in schizophrenia but not in bipolar disorder. We therefore assume that temporal imprecision and irregularity already occur in the brain's spontaneous activity in schizophrenia.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it