MétaCan
Menu
← Back to cohort
Record W4379348394 · doi:10.1017/cjn.2023.224

P.136 The effectiveness of primary endoscopic third ventriculostomy (ETV) on cognition and gait outcomes in adults with congenital obstructive hydrocephalus (COH)

2023· article· en· W4379348394 on OpenAlexaffvenueabout
Albert M. Isaacs, Carrie C. Veilleux, Mark G. Hamilton, Stefan W. Koester

Bibliographic record

VenueCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · 2023
Typearticle
Languageen
FieldNeuroscience
TopicCerebrospinal fluid and hydrocephalus
Canadian institutionsCalgary Laboratory Services
Fundersnot available
KeywordsMedicineGaitPopulationEndoscopic third ventriculostomyMontreal Cognitive AssessmentCognitionRetrospective cohort studyHydrocephalusPhysical therapyInternal medicineCognitive impairmentSurgeryPsychiatry

Abstract

fetched live from OpenAlex

Background: Endoscopic third ventriculostomy (ETV) has become a treatment of choice for adults with clinically significant chronic obstructive hydrocephalus (COH). We evaluated the impact of ETV on cognition and gait in adults with COH. Methods: We retrospectively analyzed prospectively collected data from patients who underwent ETV as primary treatment for COH. Cognitive testing using the Montreal Cognitive Assessment (MoCA) and Symbol Digit Modalities Test (SDMT) was obtained pre-ETV at three months and one year postoperatively. Gait velocity was assessed using a 10-m walk test at each time point. Results: A total of 51 patients were identified. The mean age was 55±1 years, and 45% of patients were women. Baseline MoCA was 22.6±3.1, which improved to 25.7±3.0 and 26±3.4 at three months and one year, respectively (p<0.001). Half of the patients had a normal MoCA score post-ETV (IQR 26-27 at one year, p<0.001). Gait velocity was significantly improved at three months and 1-year post-ETV (p=0.0036). The cognitive and gait improvement one year after ETV was clinically significant. Conclusions: Cognition and gait improved at three months; results were sustained at 12 months post-ETV in adult patients with COH. ETV is an efficacious surgical consideration in this population.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.248
Teacher spread0.227 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes3
Has abstractyes

Explore more

Same venueCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques→Same topicCerebrospinal fluid and hydrocephalus→French-language works237,207→