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Record W4379769649 · doi:10.1097/tp.0000000000004644

International Liver Transplantation Society Global Census: First Look at Pediatric Liver Transplantation Activity Around the World

2023· article· en· W4379769649 on OpenAlexafffund
Manuel I. Rodríguez-Dávalos, Fidel Lopez-Verdugo, Mureo Kasahara, Paolo Muiesan, Mettu Srinivas Reddy, Angel Flores-Huidobro Martinez, Qiang Xia, Johnny C. Hong, Claus U. Niemann, João Seda Neto, Tamir Miloh, Nam‐Joon Yi, George Mazariegos, Vicky L. Ng, Carlos O. Esquivel, Jan Lerut, Mohamed Rela

Bibliographic record

VenueTransplantation · 2023
Typearticle
Languageen
FieldMedicine
TopicOrgan Transplantation Techniques and Outcomes
Canadian institutionsSickKids Foundation
FundersChildren's Hospital of PittsburghKaohsiung Chang Gung Memorial HospitalCollege of Medicine, Seoul National UniversitySickkids Research InstituteMenofia UniversityUniversitair Medisch Centrum GroningenHospital for Sick ChildrenBaskent ÜniversitesiChang Gung Medical FoundationUniversity of TorontoSeoul National UniversityKing's College LondonOspedale Pediatrico Bambino GesùMedical Center, University of PittsburghUniversity of PittsburghUniversity of California, San FranciscoChildren's Hospital of PhiladelphiaRenji HospitalNational Center for Child Health and DevelopmentBharath Institute of Higher Education and ResearchAnkara Universitesi
KeywordsLiver transplantationMedicineTransplantationLiver diseaseHigh income countriesPer capitaPer capita incomeDemographyGross national incomeDeveloping countryEnvironmental healthInternal medicinePopulationEconomic growthPathology

Abstract

fetched live from OpenAlex

BACKGROUND: Over 16 000 children under the age of 15 died worldwide in 2017 because of liver disease. Pediatric liver transplantation (PLT) is currently the standard of care for these patients. The aim of this study is to describe global PLT activity and identify variations between regions. METHODS: A survey was conducted from May 2018 to August 2019 to determine the current state of PLT. Transplant centers were categorized into quintile categories according to the year they performed their first PLT. Countries were classified according to gross national income per capita. RESULTS: One hundred eight programs from 38 countries were included (68% response rate). 10 619 PLTs were performed within the last 5 y. High-income countries performed 4992 (46.4%) PLT, followed by upper-middle- (4704 [44·3%]) and lower-middle (993 [9·4%])-income countries. The most frequently used type of grafts worldwide are living donor grafts. A higher proportion of lower-middle-income countries (68·7%) performed ≥25 living donor liver transplants over the last 5 y compared to high-income countries (36%; P = 0.019). A greater proportion of programs from high-income countries have performed ≥25 whole liver transplants (52.4% versus 6.2%; P = 0.001) and ≥25 split/reduced liver transplants (53.2% versus 6.2%; P < 0.001) compared to lower-middle-income countries. CONCLUSIONS: This study represents, to our knowledge, the most geographically comprehensive report on PLT activity and a first step toward global collaboration and data sharing for the greater good of children with liver disease; it is imperative that these centers share the lead in PLT.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.214
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0010.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.285
Teacher spread0.264 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations23
Published2023
Admission routes2
Has abstractyes

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