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COGNITIVE FUNCTION IN HYPERTENSIVE PATIENTS WITH DIFFERENT TYPES OF CAROTID LESIONS

2023· article· en· W4379801837 on OpenAlexaboutno aff
Kseniia K. Kadanina, А. Е. Брагина, Valeriy Podzolkov, Natalia Druzhunina, Leila Mohammadi, Rustam Shakhmagomedov, Maxim Tyulin, Ioann Kartashov

Bibliographic record

VenueJournal of Hypertension · 2023
Typearticle
Languageen
FieldMedicine
TopicCerebrovascular and Carotid Artery Diseases
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineInternal medicineStenosisStatistical significanceMontreal Cognitive AssessmentPathologicalCognitionCarotid arteriesCardiologyGastroenterologyCognitive impairment

Abstract

fetched live from OpenAlex

Objective: The aim of our research was to study the cognitive function and its relation with the types of carotid arteries lesions (CL) in patients with hypertension. Design and method: 67 hypertensive patients (35 men and 32 women) were examined (median age 51 [45;55] y., hypertension duration 3 [2;5] y). Cognitive function was assessed by the Montreal Cognitive Rating Scale (MoCA). The subjects underwent duplex scanning of the carotid arteries on a Samsung HS50 2021. The results were statistically processed using Statistica 10 program. Results: The patients included in the study were divided into 4 groups according to the type of CL: group 1 (n = 39) without pathological carotid tortuosity (PCAT) and atherosclerotic plaques (AP); group 2 (n = 11) with PCAT, but without AP; group 3 (n = 11) with AP<70% stenosis and without PCAT, and group 4 (n = 6), which has both PCAT and AP<70% stenosis. The groups did not differ significantly in gender and age (p>0.05). Cognitive function levels were significantly higher in group 1 (28[26;29] points) when compared with group 2 (20[19;20] points, p = 0.000001), with group 3 (24[20;26] points, p = 0.00004), and with group 4 (19[19;23] points, respectively, p = 0.00009). In group 2 the MoCA level was significantly lower than in group 3 (p = 0.019). The lowest MoCA level was in group 4, though but because of the small sample of patients, the differences did not reach the level of statistical significance (p>0.05, when compared with group 2). The MoCA level was in negative correlation with the presence of CL (PCAT + AP) (r = -0.77; p<0.05). A similar correlation between the MoCA level and PCAT was in group 2 (r = -0.81; p<0.05). Conclusions: In patients with hypertension, there is a negative correlation between the cognitive function and the presence of different variants of carotid lesions. The most severe decline of cognitive function was observed in hypertensives with both atherosclerotic plaques and pathological carotid tortuosity.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.229
Teacher spread0.208 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2023
Admission routes1
Has abstractyes

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