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Record W4382241665 · doi:10.32388/oc10z4

Review of: "Depolarization block of interneurons"

2023· peer-review· en· W4382241665 on OpenAlexaff
Adam R. Stinchcombe

Bibliographic record

Venuenot available
Typepeer-review
Languageen
FieldMaterials Science
TopicSolid-state spectroscopy and crystallography
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsDepolarizationBlock (permutation group theory)NeuroscienceBiologyBiophysicsMathematicsCombinatorics

Abstract

fetched live from OpenAlex

Potential competing interests: No potential competing interests to declare.Tirozzi, Lecian, and Politi find that a published conductance-based model of hippocampal interneurons exhibits depolarization block for sufficiently large constant injected current.This loss of repetitive firing occurs through a supercritical Hopf bifurcation.Additionally, an arbitrarily small firing frequency can occur at the onset of repetitive firing showing that this neuron model is in Hodgkin's excitability class 1.There is considerable room for improvement in the exposition, grammar, and the methodology of the manuscript.Most significantly, the bifurcation analysis of the model is incomplete and the importance of the results is not clear.The manuscript needs to be improved before publication.Here are some specific comments: 1) Tirozzi should list an institutional email.2) Abstract: "of an hippocampal" "of a hippocampal", "deterministic the" "deterministic and the", "our results proved" "our results show", "are a in" "are in a", "such mechanism" "such a mechanism", "activity of the neurons" "activity of neurons".

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.019
Threshold uncertainty score0.997

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0040.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.026
GPT teacher head0.327
Teacher spread0.301 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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