Penalized logistic normal multinomial factor analyzers for high dimensional compositional data
Why this work is in the frame
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Bibliographic record
Abstract

 
 
 Model-based clustering utilizes a finite mixture model to identify underlying patterns or clusters across samples. A finite mixture model is a convex combination of two or more distributions, where appropriate distributions are chosen depending on the type of the data. Recently, there has been a great interest in clustering human microbiome data. Microbiome data are compositional (yielding relative abundance) and are high-dimensional. Previously, a family of logistic normal multinomial factor analyzers (LNM-FA) for model-based clus- tering of high-dimensional microbiome data was proposed via a factor analyzer structure. This reduced the number of parameters and computation overhead compared to a traditional mixtures of logistic normal multinomial models. Here, we propose a penalized LNM-FA (PLNM-FA) model by utilizing lasso regularization to each entry of the loading matrix. This introduces further parsimony compared to LNM-FA and also estimates the number of latent factors simultaneously. Parameter estimation is done using a variational variant of the alternating expectation conditional maximization algorithm to maximize the penalized maximum likelihood. The performance of proposed algorithm is evaluated using simula- tion studies and real data.
 Journal of Statistical Research 2022, Vol. 56, No. 2, pp.185-216 
 
 
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.003 | 0.006 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.002 | 0.001 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it