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Record W4383683837 · doi:10.58931/cibdt.2023.119

Malnutrition assessment in patients with inflammatory bowel disease

2023· article· en· W4383683837 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueCanadian IBD Today · 2023
Typearticle
Languageen
FieldMedicine
TopicNutrition and Health in Aging
Canadian institutionsUniversity of Calgary
Fundersnot available
KeywordsMalnutritionMedicineInflammatory bowel diseaseUlcerative colitisDiseaseMicronutrientMalabsorptionCrohn's diseaseMicronutrient deficiencyQuality of life (healthcare)Psychological interventionIntensive care medicineInternal medicinePathology

Abstract

fetched live from OpenAlex


 
 
 Inflammatory bowel disease (IBD) affects over 6.8 million people worldwide and is highly associated with the development of malnutrition. Malnutrition in patients with Crohn’s disease (CD) and ulcerative colitis (UC) is often due to the following: decreased oral intake; food avoidance; side effects of medications; malabsorption; chronic enteric losses; altered anatomy from luminal surgery; and increased nutritional needs in the setting of active inflammation and a high catabolic state. Approximately 20%-80% of patients with IBD are estimated to be malnourished at some point during their disease course; this wide range is likely secondary to significant heterogeneity in the definition of malnutrition in the literature, and due to the lack of robust, validated tools to identify individuals who are malnourished. While malnutrition is traditionally thought of as under- nutrition or protein calorie malnutrition, there are other nutrition phenotypes of significance in patients with IBD including micronutrient deficiencies, sarcopenia and obesity (over-nutrition). Malnutrition is associated with poor outcomes in patients with IBD, including a high number of disease flares; impaired response to biologics; increased surgical complications; hospitalizations; and impaired quality of life, independent of disease activity. Given the significant prevalence of malnutrition, the impact it can have in patients with IBD, and its responsiveness to therapeutic interventions, it is crucial to accurately assess the nutritional status of patients at the time of diagnosis and regularly thereafter.
 
 

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.022
Threshold uncertainty score0.993

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.275
Teacher spread0.262 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it