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Record W4383684677 · doi:10.58931/cect.2022.115

The evolving role of OCT in pathologic myopia

2022· article· en· W4383684677 on OpenAlexafffund
Mark Greve, Mark E. Seamone, Carl Shen

Bibliographic record

VenueCanadian Eye Care Today · 2022
Typearticle
Languageen
FieldMedicine
TopicRetinal Diseases and Treatments
Canadian institutionsWestern University
FundersDalhousie UniversityUniversity of AlbertaRoyal College of Physicians and Surgeons of CanadaUniversity of TorontoMcMaster University
KeywordsDioptreMaculopathyRefractive errorMedicineOptometryOphthalmologyOptical coherence tomographyGlaucomaMacular degenerationVisual acuityRetinopathyDiabetes mellitus

Abstract

fetched live from OpenAlex

The global burden of myopia represents a significant public health concern that is expected to continue to increase in the near future. It is estimated that 50% of the world’s population will be affected by myopia by 2050, with a disproportionately high prevalence in Asia. High myopia, where the spherical equivalent refractive error is equal to or higher than 6.00 diopters, is expected to increase in prevalence from 2.7% to 10% during this period. The severity of myopia is of paramount concern to clinicians as higher levels are associated with pathologic myopia (PM) and increased risk of vision loss. Pathologic myopia, as recently defined by the International Myopia Institute, is an excessive axial elongation associated with myopia that leads to structural changes in the posterior segment of the eye that can lead to loss of best-corrected visual acuity. These structural changes and their complications include posterior staphyloma, myopic choroidal neovascularization, myopic maculopathy, myopic traction maculopathy, dome shaped maculopathy, optic disc changes and glaucoma associated with myopia, and retinal detachments.
 The advent of optical coherence tomography (OCT) has facilitated the characterization, diagnosis, and management of several of these complications associated with PM and will be the focus of this article. Imaging the highly myopic eye represents a crucial step in the identification of these complications and poses its own unique challenges. Researchers have demonstrated the advantage of 3D cube scans in the detection of pathology compared to 1- and 5-line rasters. Using vertical scanning patterns aligning where the radius of curvature is larger relative to the horizontal plane of the myopic eye can minimize associated artifacts. Wide scans, facilitated by emerging technologies such as swept- source OCT and ultra wide-field OCT, are useful in cases of PM where the pathology can initiate peripherally.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.035
Threshold uncertainty score0.977

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.005
GPT teacher head0.235
Teacher spread0.230 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes2
Has abstractyes

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