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Record W4384433558 · doi:10.53555/sfs.v10i1.1322

Battling Blistering: A Case Report on Pemphigus Vulgaris

2023· article· en· W4384433558 on OpenAlexvenueno aff
Krishnaveni K, Ravikiran S

Bibliographic record

VenueJournal of Survey in Fisheries Sciences · 2023
Typearticle
Languageen
FieldMedicine
TopicAutoimmune Bullous Skin Diseases
Canadian institutionsnot available
Fundersnot available
KeywordsPemphigus vulgarisMedicineAzathioprineDermatologyPemphigusAcantholysisDapsoneMethotrexatePrednisoloneTacrolimusBlistersSurgeryDiseaseInternal medicineImmunologyAutoantibodyTransplantation

Abstract

fetched live from OpenAlex

  Introduction: Pemphigus is a rare group of autoimmune disorders that cause blistering of the skin and mucous membranes. It affects various parts of the body, including the eyes, genitalia, mouth, nose, and throat. The most common type of pemphigus is known as pemphigus vulgaris. It is characterized by the loss of adhesion between keratinocytes, a condition called acantholysis. Case Report: A 52-year-old male patient was admitted to the hospital with complaints of dizziness and blisters on the skin, lips, and inner layer of the mouth. Initially, he experienced difficulty in swallowing solid foods, which progressed to difficulty in swallowing liquid foods. The patient was diagnosed with pemphigus vulgaris and was treated with Methotrexate as a first-line therapy. Conclusion: According to the guidelines provided by the British Association of Dermatologists (BAD), the first-line treatment for pemphigus vulgaris involves the use of corticosteroids, typically in the form of oral prednisolone. If treatment failure occurs, defined as the lack of disease control after 12 weeks, second-line treatments such as azathioprine, MMF, methotrexate, cyclosporine, dapsone, and cyclophosphamide may be initiated. It is crucial to select the appropriate drug therapy to prevent delays in the healing of blisters and ulcers. Although there is no permanent cure for pemphigus vulgaris, medications can help reduce the severity of symptoms. Therefore, the selection of drugs plays a significant role in treating the clinical condition.  

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.005
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.081
Threshold uncertainty score0.616

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0050.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.258
GPT teacher head0.346
Teacher spread0.087 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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