MétaCan
Menu
Back to cohort
Record W4384433558 · doi:10.53555/sfs.v10i1.1322

Battling Blistering: A Case Report on Pemphigus Vulgaris

2023· article· en· W4384433558 on OpenAlexvenueno aff
Krishnaveni K, Ravikiran S

Bibliographic record

VenueJournal of Survey in Fisheries Sciences · 2023
Typearticle
Languageen
FieldMedicine
TopicAutoimmune Bullous Skin Diseases
Canadian institutionsnot available
Fundersnot available
KeywordsPemphigus vulgarisMedicineAzathioprineDermatologyPemphigusAcantholysisDapsoneMethotrexatePrednisoloneTacrolimusBlistersSurgeryDiseaseInternal medicineImmunologyAutoantibodyTransplantation

Abstract

fetched live from OpenAlex

Introduction: Pemphigus is a rare group of autoimmune disorders that cause blistering of the skin and mucous membranes. It affects various parts of the body, including the eyes, genitalia, mouth, nose, and throat. The most common type of pemphigus is known as pemphigus vulgaris. It is characterized by the loss of adhesion between keratinocytes, a condition called acantholysis. Case Report: A 52-year-old male patient was admitted to the hospital with complaints of dizziness and blisters on the skin, lips, and inner layer of the mouth. Initially, he experienced difficulty in swallowing solid foods, which progressed to difficulty in swallowing liquid foods. The patient was diagnosed with pemphigus vulgaris and was treated with Methotrexate as a first-line therapy. Conclusion: According to the guidelines provided by the British Association of Dermatologists (BAD), the first-line treatment for pemphigus vulgaris involves the use of corticosteroids, typically in the form of oral prednisolone. If treatment failure occurs, defined as the lack of disease control after 12 weeks, second-line treatments such as azathioprine, MMF, methotrexate, cyclosporine, dapsone, and cyclophosphamide may be initiated. It is crucial to select the appropriate drug therapy to prevent delays in the healing of blisters and ulcers. Although there is no permanent cure for pemphigus vulgaris, medications can help reduce the severity of symptoms. Therefore, the selection of drugs plays a significant role in treating the clinical condition.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.016

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0040.002
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0050.004
Science and technology studies0.0040.003
Scholarly communication0.0030.004
Open science0.0020.003
Research integrity0.0070.005
Insufficient payload (model declined to judge)0.0050.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.258
GPT teacher head0.346
Teacher spread0.087 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

Explore more

Same venueJournal of Survey in Fisheries SciencesSame topicAutoimmune Bullous Skin DiseasesFrench-language works237,207