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Global population structure in an arctic-breeding bird: Diversifying and stabilizing selection consistent with local adaptation

2023· preprint· en· W4385142860 on OpenAlexafffund
Keta Patel, Oliver P. Love, Kyle W. Wellband, Audrey Le Pogam, François Vézina, Noah T. Ashley, Frode Fossøy, Kevin Winker, Melanie M. Richter, H. Grant Gilchrist, Arne Moksnes, Bård G. Stokke, Jack J. Withrow, Daniel D. Heath

Bibliographic record

Venuenot available
Typepreprint
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic diversity and population structure
Canadian institutionsEnvironment and Climate Change CanadaUniversité du Québec à RimouskiUniversité LavalUniversity of Windsor
FundersNatural Sciences and Engineering Research Council of CanadaEnvironment and Climate Change CanadaCanada Research ChairsArcticNetGovernment of OntarioUniversity of WindsorArctic Institute of North America
KeywordsBiologyLocal adaptationPopulationGenetic divergenceEvolutionary biologyGenetic structureSelection (genetic algorithm)MicrosatelliteGeneticsGenetic variationGenetic diversityAlleleGene

Abstract

fetched live from OpenAlex

Environmental variation among isolated populations can drive genetic differentiation by selection, while isolation alone results primarily in genetic drift. Genetic analyses can aid in identifying genetically isolated populations and population structure of a species across its range. Additionally, such analyses can provide indirect evidence of local adaptation through the comparison of allele frequencies at neutral and functional genetic markers, with the aim of identifying outlier loci consistent with the effects of selection. Here, we examine the genetic divergence and patterns of functional divergence among six breeding populations of arctic-breeding snow buntings (Plectrophenax nivalis). We genotyped 221 birds at 9 microsatellite markers and at 101 single nucleotide polymorphisms (SNPs) located within known-function genes. We identified substantial population differentiation using both marker types with relatively greater divergence and hence finer population structure using the microsatellite markers. While population structures resulting from the two marker types were in general agreement, functional SNPs showed evidence of stabilizing selection at both global and population pairwise levels, with a few key SNPs showing signatures of pairwise divergent selection, consistent with expectations of local adaptation. The observed complex and inconsistent pattern of pairwise divergence (selection) at key candidate-gene loci may reflect rapid environmental change decoupling locally adapted genotypes from actual local environmental conditions. Our work highlights microevolutionary changes that are likely to be very important not only in arctic-breeding songbirds, but in Arctic and Sub-Arctic vertebrates in general, which are experiencing strong environmental effects from accelerated climate change and human-induced stressors.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.035
GPT teacher head0.263
Teacher spread0.227 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes2
Has abstractyes

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